Biochemistry Questions and Answers – The Covalent Structure of Proteins

This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “The Covalent Structure of Proteins”.

1. Which of the following statements is false?
a) Primary structure of a protein determines how it folds up into a unique three dimensional structure
b) Secondary structure of a protein determines how it folds up into a unique three dimensional structure
c) Three dimensional structure of a protein determines the function of a protein
d) Amino acid sequence is absolutely invariant for a particular protein
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2. Who deduced the double-helical structure of DNA?
a) Frederick Sanger
b) Mendel
c) Watson and Francis Crick
d) Anton van Leeuwenhoek
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3. Two chains of amino acids in an insulin molecule are held together by __________
a) Sulfide bridges
b) Disulfide bridges
c) Peptide bond
d) Covalent linkage
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4. Tertiary conformation of proteins is maintained by 3 types of bonds namely ionic, hydrogen and __________
a) Sulfide
b) Disulfide
c) Covalent
d) Peptide
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5. Hemoglobin is a __________
a) Monomer
b) Dimer
c) Trimer
d) Tetramer
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6. Which of the following is false?
a) The two main types of secondary structure are the α helix and β pleet structures
b) α helix is a right handed coiled strand
c) The hydrogen bonding in a β-sheet is between strands rather than within strands
d) The hydrogen bonding in a β-sheet is within strands rather than between strands
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7. Native state of a protein can be disrupted by __________
a) Temperature
b) pH
c) Removal of water
d) Presence of hydrophilic surfaces
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8. Which of the following is true?
a) The disulfide bridges formed by reduction of the sulfhydryl groups on cysteine stabilizes protein tertiary structure
b) The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine destabilizes protein tertiary structure
c) The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine stabilizes protein tertiary structure
d) The disulfide bridges formed by reduction of the sulfhydryl groups on cysteine destabilizes protein tertiary structure
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9. Identify the wrong statement.
a) Hemoglobin is a globular protein
b) Hemoglobin is a fibrous protein
c) Fibrous proteins are insoluble in water
d) Collagen is a fibrous protein
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10. In 3° structure of proteins, folding and shaping is done by __________
a) Hydrophobic interactions
b) Polar interactions
c) Hydrogen bonding
d) None of the mentioned
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Sanfoundry Global Education & Learning Series – Biochemistry.

To practice all areas of Biochemistry, here is complete set of 1000+ Multiple Choice Questions and Answers.

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