This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “Principles of Gene Regulation”.
1. Which of the following is not an example of housekeeping genes?
a) RNA polymerase
b) r-RNA genes
c) Beta galactosidase
d) Enzymes required for basic metabolic pathways common to most cells
View Answer
Explanation: Enzymes required for basic metabolic pathways common to most cells are housekeeping genes; RNA polymerase and r-RNA genes are the examples.
2. Lactose utilization by E. coli requires ____________
a) Lac-Z
b) Lac-A
c) Lac-Y
d) Lac-l
View Answer
Explanation: Lactose utilization by E. coli requires lac-Y.
3. The lactose repressor is encoded by ____________
a) Lac-l
b) Lac-A
c) Lac-Y
d) Lac-Z
View Answer
Explanation: Lac-l encodes lactose repressor.
4. Where does a repressor bind an operon?
a) Operator
b) Promoter
c) Inducer
d) Catabolite activator site
View Answer
Explanation: Repressor binds an operon at the operator.
5. Lac repressor dissociates from its operator when the repressor binds to ____________
a) Heat shock module
b) Promoter
c) Inducer
d) Catabolite activator site
View Answer
Explanation: The Lac repressor dissociates from its operator when the repressor binds to its inducer, allolactose.
6. The lac repressor has which of the following DNA-binding motif?
a) Helix-turn-helix
b) Zinc finger
c) Homeodomain
d) Leucine zipper
View Answer
Explanation: The lac repressor has helix-turn-helix DNA-binding motif.
7. Which of the following are the structural motifs that mediate protein-protein interactions?
a) Leucine zipper and basic helix-loop-helix
b) Homeodomain
c) Zinc finger
d) Helix-turn-helix
View Answer
Explanation: Leucine zipper will mediate protein interaction facilitates the dimerization of the protein by interdigitation of two leucine-containing helices on different molecules.
8. If lactose and glucose are provided in the growth medium of a culture of E. coli ____________
a) Lactose operon is not transcribed
b) Lactose metabolism is favored
c) Both lactose and glucose are metabolized at same rate
d) Adenylate cyclase is activated
View Answer
Explanation: If lactose and glucose are provided in the growth medium of a culture of E. coli lactose operon is not transcribed.
9. Which of the following is not required for the expression of genes in the lactose operon?
a) lacl gene product
b) cAMP
c) Allolactose
d) Adenylate cyclase
View Answer
Explanation: cAMP, allolactose and adenylate cyclase are required for the expression of genes in the lactose operon.
10. Which out of the following is not an example of an inducible operon?
a) Lactose operon
b) Galactose operon
c) Maltose operon
d) Tryptophan operon
View Answer
Explanation: Lactose operon, galactose operon and maltose operon are examples of the inducible operon.
Sanfoundry Global Education & Learning Series – Biochemistry.
To practice all areas of Biochemistry, here is complete set of 1000+ Multiple Choice Questions and Answers.
- Check Biochemistry Books
- Practice Biotechnology MCQs
- Apply for Biotechnology Internship
- Check Biotechnology Books