Biochemistry Questions and Answers – Composition and Architecture of Membranes

This set of Basic Biochemistry Questions and Answers focuses on “The Composition and Architecture of Membranes”.

1. Which of the following acts as a passive electrical insulator?
a) Myelin sheath
b) Plasma membrane
c) Inner mitochondrial membrane
d) Outer mitochondrial membrane
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2. Which of the following membranes contain low cholesterol and high cardiolipin?
a) Myelin sheath
b) Plasma membrane
c) Inner mitochondrial membrane of hepatocyte
d) Cell wall
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3. Which of the following is important in signal transduction triggered by hormones?
a) Phosphatidylinositol and its derivatives
b) Phosphatidylserine and its derivatives
c) Phosphatidylglycerol and its derivatives
d) Phosphatidylethanolamine
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4. Which of the following are the major component of chloroplast membrane of plants and are absent from animal cells?
a) Glycolipids
b) Phospholipids
c) Ether lipids
d) Triacylglycerols
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5. How many types of lipid aggregates are formed when amphipathic lipids are mixed with water?
a) 1
b) 2
c) 3
d) 4
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6. Which of the following types of lipid aggregates has maximum stability?
a) Micelles
b) Bilayer
c) Liposome
d) Myelin sheath
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7. When cross sectional area of the head group and acyl side chain is similar, which of the following lipid aggregates formation is favored?
a) Micelles
b) Bilayer
c) Liposome
d) Myelin sheath
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8. When cross sectional area of the head group is greater than that of the acyl side chain, which of the following lipid aggregates formation is favored?
a) Micelles
b) Bilayer
c) Liposome
d) Myelin sheath
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9. Which of the following is choline containing lipid?
a) Sphingomyelin
b) Phosphatidylserine
c) Phosphatidylglycerol
d) Phosphatidylethanolamine
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10. A platelet is able to play its role in the formation of blood clot when one of the glycerophospholipids in the plasma membrane moves into the outer leaflet.
a) Phosphatidylserine
b) Phosphatidylethanolamine
c) Phosphatidylinositol
d) Phosphatidylglycerol
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11. Which of the following glycerophospholipids is not common in inner leaflet (cytoplasmic)?
a) Phosphatidylserine
b) Phosphatidylethanolamine
c) Phosphatidylinositol
d) Phosphatidylcholine
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12. Which of the following has high lipid content?
a) Myelin sheath
b) Plasma membrane
c) Inner mitochondrial membrane
d) Outer mitochondrial membrane
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13. Plasma membrane is permeable to __________
a) ATP
b) Glucose
c) K⁺
d) Urea
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14. How are the intrinsic proteins in cell membrane distributed?
a) Uniform
b) Random
c) Symmetric
d) Asymmetric
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