This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “RNA-Dependent Synthesis of RNA and DNA”.
1. An example of RNA-dependent DNA polymerase is
a) Reverse transcriptase
b) DNA ligase
c) RNA polymerase I
d) RNA polymerase II
Explanation: RNA polymerase I, RNA polymerase II are DNA dependent RNA polymerases and DNA ligase is ATP-dependent.
2. Reverse transcriptase does not catalyze
a) RNA-dependent DNA synthesis
b) RNA degradation
c) DNA-dependent DNA synthesis
d) DNA-dependent RNA synthesis
Explanation: Reverse transcriptase catalyzes three different reactions: RNA-dependent DNA synthesis, RNA degradation and DNA-dependent DNA synthesis.
3. Which of the following are not DNA viruses?
a) Hepatitis B virus
b) Influenza A virus
c) CMV virus
Explanation: Influenza A virus is RNA virus.
4. Which of the following statements about viruses is true?
a) They contain DNA
b) They contain RNA
c) They contain protein
d) They are susceptible to lipid solvents
Explanation: They contain either DNA or RNA. Only enveloped viruses are susceptible to lipid solvents.
5. The enzyme used in the formation of cDNA from mRNA is
c) Reverse transcriptase
Explanation: Reverse transcriptases make possible the synthesis of DNA complementary to an mRNA template.
6. Which of the following solves the problem of shortening of chromosomes in each cell cycle?
a) DNA ligase
d) RNA polymerase
Explanation: Telomerase adds telomeres to chromosome ends and solve the problem of chromosomes shortening.
7. Which of the following is RNA-dependent RNA polymerase?
a) Reverse transcriptase
b) RNA polymerase I
c) RNA polymerase II
d) RNA replicase
Explanation: RNA polymerase I, RNA polymerase II are DNA dependent RNA polymerases and reverse transcriptase is RNA-dependent DNA polymerase.
8. HIV may not respond to
a) Nucleoside analogues
b) Protease inhibitors
c) Neuraminidase inhibitors
d) Reverse transcriptase inhibitors
Explanation: Neuraminidase inhibitors are used for the treatment of influenza virus.
9. Which of the following introns have self-splicing activity?
a) Group I and group II
b) Group II and group III
c) Group III and group IV
d) Group I and group III
Explanation: Only group I and group II introns have self-splicing activity.
10. Which type of homing is DNA-based?
a) Group I intron
b) Group II intron
c) Group III intron
d) Group IV intron
Explanation: Group II intron homing occurs through an RNA intermediate.
Sanfoundry Global Education & Learning Series – Biochemistry.
To practice all areas of Biochemistry, here is complete set of 1000+ Multiple Choice Questions and Answers.