Biochemistry Questions and Answers – Nucleotides & Nucleic Acids Basics

This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “Nucleotides & Nucleic Acids Basics”.

1. Identify the purine base of nucleic acids in the following.
a) Cytosine
b) Thymine
c) Uracil
d) Adenine
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2. Which of the following are not the components of RNA?
a) Thymine
b) Adenine
c) Guanine
d) Cytosine
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3. Which of the following statements is true?
a) Sugar component of a nucleotide is ribose
b) Sugar component of a nucleotide is deoxyribose
c) The bases in nucleotides are attached to a pentose sugar moiety by a glycosidic linkage
d) The sugar molecule of the nucleotide is in L-configuration
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4. What is the composition of nucleoside?
a) a sugar + a phosphate
b) a base + a sugar
c) a base + a phosphate
d) a base + a sugar + phosphate
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5. What is the composition of nucleotide?
a) a sugar + a phosphate
b) a base + a sugar
c) a base + a phosphate
d) a base + a sugar + phosphate
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6. Group of adjacent nucleotides are joined by ____________
a) Phosphodiester bond
b) Peptide bond
c) Ionic bond
d) Covalent bond
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7. The sugar molecule in a nucleotide is ____________
a) Pentose
b) Hexose
c) Tetrose
d) Triose
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8. Which of the following is true about phosphodiester linkage?
a) 5’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide
b) 3’-phosphate group of one nucleotide unit is joined to the 5’-hydroxyl group of the next nucleotide
c) 5’-phosphate group of one nucleotide unit is joined to the 5’-hydroxyl group of the next nucleotide
d) 3’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide
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9. Which of the following is false about purine and pyrimidine bases?
a) They are hydrophobic and relatively insoluble in water at the near-neutral pH of the cell
b) At acidic or alkaline pH the bases become charged and their solubility in water increases
c) Purines have two rings in their structure, but pyrimidine bases have only one ring
d) At acidic or alkaline pH the bases become charged and their solubility in water decreases
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10. Building blocks of nucleic acids are ____________
a) Nucleotides
b) Nucleosides
c) Amino acids
d) Histones
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Sanfoundry Global Education & Learning Series – Biochemistry.

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