Membrane Phospholipids Biosynthesis - Biochemistry Questions and Answers

This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “Biosynthesis of Membrane Phospholipids”.

1. Displacement of CMP through nucleophilic attack by the hydroxyl group of serine yields ___________
a) Phosphatidyl serine
b) Phosphatidyl glycerol 3-phosphate
c) Phosphatidyl glycerol
d) Phosphatidylethanolamine
View Answer

Answer: a
Explanation: Displacement of CMP through nucleophilic attack by the hydroxyl group of serine yields phosphatidyl serine.

2. Displacement of CMP through a nucleophilic attack by the hydroxyl group of C-1 hydroxyl of glycerol 3-phosphate yields ___________
a) Phosphatidyl serine
b) Phosphatidyl glycerol 3-phosphate
c) Phosphatidyl glycerol
d) Phosphatidylethanolamine
View Answer

Answer: b
Explanation: Displacement of CMP through nucleophilic attack by the hydroxyl group of C-1 hydroxyl of glycerol 3-phosphate yields phosphatidyl glycerol 3-phosphate.

3. Which of the following is a molecular formula of cholesterol?
a) C₂₇H₄₅OH
b) C₂₈H₄₅OH
c) C₂₉H₄₅OH
d) C₂₃H₄₅OH
View Answer

Answer: a
Explanation: C₂₇H₄₅OH is the molecular formula of cholesterol.

4. Which of the following is involved in the bio-signaling pathway that includes membrane turnover and exocytosis?
a) Phosphatidylinositol
b) Phosphatidyl glycerol
c) Myoinositol
d) Phosphatidyl glycerol and myoinositol
View Answer

Answer: a
Explanation: Phosphatidylinositol is involved in the bio-signaling pathway that includes membrane turnover and exocytosis.

5. The precursor of eicosanoids in human is ___________
a) Ceramide
b) Arachidonic acid
c) Cholesterol
d) Squaline
View Answer

Answer: b
Explanation: The precursor of eicosanoids in human is arachidonic acid.

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6. Which of the following is the simplest hydrophilic moiety present in membrane lipids?
a) Glucose
b) Amino group
c) Hydroxyl group
d) Phosphate group
View Answer

Answer: c
Explanation: Hydroxyl group is the simplest hydrophilic moiety present in membrane lipids.

7. Which of the following is considered as the structural parent of all sphingolipids?
a) Sphingosine
b) Ceramide
c) Lecithin
d) Sphingomyelin
View Answer

Answer: b
Explanation: N-acyl fatty acid derivative of sphingosine at C2 is called ceramide, which forms the backbone of sphingolipids.

8. The most complex sphingolipid is ___________
a) Cerebroside
b) Gangleoside
c) Globoside
d) Ceramide
View Answer

Answer: b
Explanation: Gangleosides have the most complex structure.

9. Phosphatidylserine is derived only from ___________
a) Phosphatidylethanolamine
b) Phosphatidyl glycerol
c) Phosphatidyl choline
d) CDP-diacylglycerol
View Answer

Answer: a
Explanation: Decarboxylation of phosphatidylserine produces phosphatidylethanolamine.

10. Cerebroside is also called as ___________
a) Sphingomyelin
b) N-acylsphingosine
c) Sphinganine
d) Gangliosides
View Answer

Answer: a
Explanation: Cerebroside is also called as sphingomyelin.

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