Biochemistry Questions and Answers – Regulation of Metabolic Pathways

This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “Regulation of Metabolic Pathways”.

1. Which out of the following statements is true about the regulation of metabolic pathway?
a) Most of the metabolic pathways are regulated
b) Most of the metabolic pathways are not regulated
c) Regulation of metabolic pathways always involves changing the amount of enzymes
d) Metabolic regulation always depends on control by hormones
View Answer

Answer: a
Explanation: According to the physiological needs, rate of metabolism needs to be changed.

2. The rate of breakdown of metabolites is termed as ___________
a) Metabolic state
b) Metabolism
c) Steady state
d) Homeostasis
View Answer

Answer: c
Explanation: The rate of breakdown of metabolites is termed as a steady state.

3. Diminished delivery of oxygen to tissues is termed as ___________
a) Hypoxia
b) Ischemia
c) Homeostasis
d) Metabolism
View Answer

Answer: a
Explanation: Diminished delivery of oxygen to tissues is termed as hypoxia.
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4. Diminished flow of blood to tissues is termed as ___________
a) Hypoxia
b) Ischemia
c) Homeostasis
d) Metabolism
View Answer

Answer: b
Explanation: Diminished flow of blood to tissues is termed as ischemia.

5. Which of the following statements is true about the control of muscle glycogen phosphorylase?
a) It is activated by phosphorylation by an active phosphorylase kinase
b) It is allosterically activated by ATP
c) It is allosterically activated by cAMP
d) Normally it exists in active form
View Answer

Answer: a
Explanation: It is allosterically inhibited by ATP. It is partially activated allosterically by AMP. Normally it exists in inactive form.
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6. Which of the following is not a factor determining the activity of an enzyme?
a) Association with regulatory protein
b) Sequestration
c) Allosteric regulation
d) Nucleotides
View Answer

Answer: d
Explanation: Association with regulatory protein, sequestration, allosteric regulation and covalent modification are the factors determining the activity of an enzyme.

7. Which of the following statements is true?
a) High insulin/glucagon ratio activates lipolysis in muscle
b) High insulin/glucagon ratio inhibits lipolysis in liver
c) High insulin/glucagon ratio activates lipolysis in adipocytes
d) Low insulin/glucagon ratio activates lipolysis in adipocytes
View Answer

Answer: d
Explanation: A high insulin/glucagon inactivates lipolysis.
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8. Which of the following type of metabolites is used for generating glucose under severe starvation conditions?
a) Amino acids
b) Fats
c) Glycogen
d) Starch
View Answer

Answer: a
Explanation: Fats cannot be converted to glucose; there is no store of carbohydrate. Only amino acids can be used for generating glucose under severe starvation conditions.

9. Which of the following statements is true about brain metabolism in starvation?
a) The brain can use glucogenic amino acids for energy
b) The brain can only use glucose as fuel
c) Up to a quarter of energy requirement of the brain can come from fatty acids
d) Up to a half of energy requirement of the brain can come from ketone bodies
View Answer

Answer: a
Explanation: Brain does not use amino acids directly but glucose derived from glucogenic amino acids in the liver.
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10. Which one of the following statements about the control of enzyme activity by phosphorylation is correct?
a) Phosphorylation of an enzyme results in a conformational change
b) Phosphorylation of an enzyme occurs only at specific tyrosine residues
c) Phosphorylation of an enzyme is carried out by phosphoprotein phosphatases
d) Enzyme control by phosphorylation is irreversible
View Answer

Answer: a
Explanation: Phosphorylation of enzyme is reversible; phosphorylation is not carried out by phosphoprotein phosphatases.

Sanfoundry Global Education & Learning Series – Biochemistry.

To practice all areas of Biochemistry, here is complete set of 1000+ Multiple Choice Questions and Answers.

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Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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