This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “The Genetic Code”.
1. A codon contains how many nucleotides?
a) 1
b) 2
c) 3
d) 4
View Answer
Explanation: A codon is a triplet of nucleotides that codes for a specific amino acid.
2. The initiation codon is ____________
a) AUG
b) UAA
c) UAG
d) UGA
View Answer
Explanation: UAA, UAG and UGA are termination codons.
3. The termination codon is not ____________
a) AUG
b) UAA
c) UAG
d) UGA
View Answer
Explanation: AUG is an initiation codon.
4. How many t-RNAs are required to translate all 61 codons?
a) 31
b) 32
c) 30
d) 29
View Answer
Explanation: A minimum of 32 t-RNAs are required to translate all 61 codons.
5. Which position of a codon is said to wobble?
a) First
b) Second
c) Third
d) Fourth
View Answer
Explanation: 3rd position is said to wobble in codon. Binding of a codon in an mRNA the cognate tRNA is much “looser” in the third position of the codon. This permits several types of non-Watson–Crick base pairing to occur at the third codon position.
6. In which of the following cases the first base of anticodon pairs with only one codon?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer
Explanation: When the first base of the anticodon is C or A, base pairing is specific and only one codon is recognized by that t-RNA.
7. In which of the following cases the first base of anticodon pairs with two codons?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer
Explanation: When the first base of the anticodon is G or U, base pairing is less specific and two different codons may be read.
8. In which of the following cases the first base of anticodon pairs with three codons?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer
Explanation: When inosine is the first nucleotide of an anticodon, three different codons can be recognized.
9. The genetic code translated the language of ____________
a) Proteins into that of RNA
b) Amino acids into that of RNA
c) RNA into that of proteins
d) RNA into that of DNA
View Answer
Explanation: The overall process of mRNA-guided protein synthesis is often referred to simply as translation.
10. Wobble hypothesis was first proposed by ____________
a) Nirenberg
b) Watson and Crick
c) Watson
d) Crick
View Answer
Explanation: Crick proposed a set of four relationships called the wobble hypothesis.
Sanfoundry Global Education & Learning Series – Biochemistry.
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