Biochemistry Questions and Answers – The Genetic Code

This set of Biochemistry Multiple Choice Questions & Answers (MCQs) focuses on “The Genetic Code”.

1. A codon contains how many nucleotides?
a) 1
b) 2
c) 3
d) 4
View Answer

Answer: c
Explanation: A codon is a triplet of nucleotides that codes for a specific amino acid.

2. The initiation codon is ____________
a) AUG
b) UAA
c) UAG
d) UGA
View Answer

Answer: a
Explanation: UAA, UAG and UGA are termination codons.

3. The termination codon is not ____________
a) AUG
b) UAA
c) UAG
d) UGA
View Answer

Answer: a
Explanation: AUG is an initiation codon.
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4. How many t-RNAs are required to translate all 61 codons?
a) 31
b) 32
c) 30
d) 29
View Answer

Answer: b
Explanation: A minimum of 32 t-RNAs are required to translate all 61 codons.

5. Which position of a codon is said to wobble?
a) First
b) Second
c) Third
d) Fourth
View Answer

Answer: c
Explanation: 3rd position is said to wobble in codon. Binding of a codon in an mRNA the cognate tRNA is much “looser” in the third position of the codon. This permits several types of non-Watson–Crick base pairing to occur at the third codon position.
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6. In which of the following cases the first base of anticodon pairs with only one codon?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer

Answer: a
Explanation: When the first base of the anticodon is C or A, base pairing is specific and only one codon is recognized by that t-RNA.

7. In which of the following cases the first base of anticodon pairs with two codons?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer

Answer: d
Explanation: When the first base of the anticodon is G or U, base pairing is less specific and two different codons may be read.
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8. In which of the following cases the first base of anticodon pairs with three codons?
a) When the first base of anticodon is A or C
b) When the first base of anticodon is A or G
c) When the first base of anticodon is inosine
d) When the first base of anticodon is G or U
View Answer

Answer: c
Explanation: When inosine is the first nucleotide of an anticodon, three different codons can be recognized.

9. The genetic code translated the language of ____________
a) Proteins into that of RNA
b) Amino acids into that of RNA
c) RNA into that of proteins
d) RNA into that of DNA
View Answer

Answer: c
Explanation: The overall process of mRNA-guided protein synthesis is often referred to simply as translation.
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10. Wobble hypothesis was first proposed by ____________
a) Nirenberg
b) Watson and Crick
c) Watson
d) Crick
View Answer

Answer: d
Explanation: Crick proposed a set of four relationships called the wobble hypothesis.

Sanfoundry Global Education & Learning Series – Biochemistry.

To practice all areas of Biochemistry, here is complete set of 1000+ Multiple Choice Questions and Answers.

If you find a mistake in question / option / answer, kindly take a screenshot and email to [email protected]

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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