This set of Bioseparation Technology Multiple Choice Questions & Answers (MCQs) focuses on “Economic Importance of Bioseparation”.
1. What is the feasibility of purification of biological products?
a) Difficult and expensive
b) Easy and cost effective
c) Difficult and cost effective
d) Easy and expensive
View Answer
Explanation: The purification of biological products is technically difficult and expensive process and it acts as a critical limiting factor in the commercialization of the biological products.
2. Purification cost of which biological product is quite substantial?
a) Proteins and nucleic acid
b) Solvents
c) Monoclonal antibodies
d) Antibiotics
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Explanation: The purification cost of nucleic acids and proteins is quite substantial, especially those used in biopharmaceuticals than any other approach. These products are complex and results in by – product formation therefore its purification is quite substantial.
3. The product having least bioseparation cost is ___________
a) proteins and nucleic acid
b) solvents
c) monoclonal antibodies
d) antibiotics
View Answer
Explanation: The bioseparation cost of solvent is 15-20 % of the overall cost utilized in the bioprocess both of upstream and downstream process. Solvents can be easily purified and have no formation of by-products therefore bioseparation cost is minimum.
4. The bioseparation cost of vitamins and amino acids are __________
a) 30-40%
b) 40-50%
c) 10-20%
d) 70-80%
View Answer
Explanation: The bioseparation cost of vitamins and amino acids are 30-40% of the overall cost utilized in the bioprocess both of upstream and downstream process. The purification of vitamins and amino acid doesn’t require much costing as compared to proteins and nucleic acids.
5. What is the importance of bioseparation?
a) Enrichment of target products, achievement of product specification, reduction in bulk
b) Reduction in bulk, achievement of product specification, prevention of product degradation
c) Removal of impurities, prevention of product degradation, reduction in bulk
d) Enrichment of target products, achievement of product specification, reduction in bulk, removal of impurities, prevention of product degradation
View Answer
Explanation: The bioseparation is important as it helps in Enrichment of target products, achievement of product specification, reduction in bulk, removal of impurities and prevention of product degradation. Bioseparation is the need of an hour since all the products we use needs to be purified before usage.
6. The important factors for the designing of bioseparation are _________
a) purity, cost, market
b) usability, market, enzyme
c) purity, enzyme, chemical
d) usability, cost, chemical
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Explanation: The factors important for the designing of bioseparations are purity, cost and market. All three are the vital criteria to fix before designing a setup for bioseparation. The cost of bioseparation depends on the product being purified and its market value.
7. What are the characteristics of best bioseparation setup?
a) Ensure product purity, stability, cost effectiveness
b) Ensure non-reproducibility, costly, instability of the product
c) Ensure product degradation, partial purity, reproducibility
d) Ensure high market value, instability, purity of the product
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Explanation: The best bioseparation setup should ensure product purity, should provide stable products, the process must be cost effective and the products can be reproduced and should meet regulatory guidelines.
8. What is the bioseparation cost of antibiotic penicillin?
a) 20-30%
b) 50-60%
c) 40-50%
d) 10-15%
View Answer
Explanation: The bioseparation cost of antibiotic penicillin is 20-30% of total cost. The approximate relative cost of production is 60% out of which 30% is required for the bioseparation.
9. What is the bioseparation cost of ethanol?
a) 15%
b) 20%
c) 30%
d) 40%
View Answer
Explanation: The bioseparation cost of antibiotic penicillin is 15% of total cost. The 15% cost is required for the bioseparation out of the approximate relative cost of production.
10. What is the bioseparation cost of bulk enzymes?
a) 40-65%
b) 50-70%
c) 70-75%
d) 75-80%
View Answer
Explanation: The bioseparation cost of bulk enzymes is 40-65% of total cost. The approximate relative cost of production is 100% out of which 65% is required for the bioseparation.
Sanfoundry Global Education & Learning Series – Bioseparation Technology.
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