This set of Pharmaceutical Biotechnology Multiple Choice Questions & Answers (MCQs) focuses on “Formulations”.
1. What do you mean by drug formulation?
a) The process of manufacturing drugs in an industrial scale
b) The process in which the manufactured drugs are stabilized by altering their chiral centers
c) The process in which various chemical components along with the active drug is combined together to form a medicinal product
d) The process of granulating the drug products in order to improve its flow characteristics
View Answer
Explanation: Drug formulation is defined as the process of producing medicinal drug products by combining different chemical substances of definite proportions. It is considered as the foremost step in research and development of new drugs.
2. Which of the following is not taken into account while determining the type of drug formulation?
a) Age and Gender
b) Health issues/conditions
c) Route of administration
d) Body mass index
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Explanation: Body mass index (BMI) is not taken into account while formulating a drug, but it is essential to consider the patient’s age, gender and health conditions. In addition to these, the process of drug formulation is also depended upon the route of administration to achieve specificity.
3. Solid drug formulations are easily absorbed within our body than other physical drug formulations.
a) True
b) False
View Answer
Explanation: Drug Formulation can be classified based on its Physical form (such as solid, liquid, or gas) and Route of administration. Generally, drugs incorporated in solid formulations are not readily absorbed when compared to other liquid and gaseous forms.
4. Which of the following does not falls under semi-solid drug formulation?
a) Oral Preparations
b) Sustained Release Preparations
c) Topical Preparations
d) Sublingual and Buccal Administration
View Answer
Explanation: Sustained Release Preparation is a type of solid formulation, whereas, all the other options come under semi-solid drug formulation. In Sustained Release Preparations, only a fixed active drug concentration is released over a time period.
5. Which of the following is not a type of controlled release drugs?
a) Pulse-release
b) Unintended-release
c) delayed-release
d) extended-release
View Answer
Explanation: The three main types of controlled-release drug forms are pulse-release, extended-release and delayed-release. Controlled release drugs are prescribed when there is a need to release the active components of the drug at a prespecified time.
6. The drug Insulin is administered through which parenteral mode?
a) Intradermal
b) Intravenous
c) Subcutaneous
d) Intramuscular
View Answer
Explanation: As Insulin cannot be given through oral dosage, it is administered into the body by injecting the drug within the subcutaneous layer under the skin. This mode of administration is also effective for vaccines.
7. Which of the following is not a tablet form?
a) Hard Cold Tablet
b) Sugar Coated Tablets
c) Dispersible Tablets
d) Multilayer Tablets
View Answer
Explanation: Except Hard Cold Tablet, all the other tablet forms are available and are prescribed based on their usage and administration. But, on the contrary, Soft Cold Tablet, which is a combination of three medicines, is widely used to provide relief from common cold.
8. The term drug formulation is frequently used while describing dosage forms.
a) True
b) False
View Answer
Explanation: Dosage form denotes the physical characteristic feature of a drug. This enables drugs to be prescribed based on the route of administration. Hence the term formulation is often involved while describing dosage forms.
9. Which site is most commonly used for intradermal administration?
a) Lateral hip
b) Thigh
c) Forearm
d) Upper buttock
View Answer
Explanation: Forearm, which has the deltoid muscle, is the common site for administering intradermal injections. Generally, intradermal medications are injected into the upper layer of dermis and this mode of drug administration is highly suitable for vaccines and local anesthetics.
10. Which of the following is not true about lozenges?
a) They are tablets
b) They disintegrate quickly
c) They usually have sweetened base containing proportion of drugs
d) They shouldn’t be swallowed
View Answer
Explanation: Lozenges, also known as cough drops, are tablets which has a base of sugar that are specifically designed to dissolve slowly in the mouth. They are involved in treating sore throat and also helps in reducing cough.
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