Tissue Engineering Questions and Answers – Biomaterial -Tissue Interactions

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This set of Tissue Engineering Multiple Choice Questions & Answers (MCQs) focuses on “Biomaterial -Tissue Interactions”.

1. What is the first step in Biomaterial-tissue interactions?
a) Cell Migration
b) Adsorption of proteins
c) Cell Development
d) Cell adhesion
View Answer

Answer: d
Explanation: The initial phase in biomaterial–tissue connection is the underlying adsorption of proteins onto the outside of the biomaterial, which, in a mix with the physical and multiple properties of the surface, is thought to prompt ensuing cell practices, for example, bond, spreading and expansion.
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2. The biomaterials are expected to mimic the functions of ____________
a) Extracellular Matrix (ECM)
b) Transmembrane proteins
c) Cytoplasm
d) Cell Organelles
View Answer

Answer: a
Explanation: TE depends on platform biomaterials that will have cells from the body and, with the assistance of development factors or a bioreactor, will ideally prompt tissue regeneration. These biomaterials are subsequently expected to mirror the ECM capacities and connections with the cells and the encompassing tissues. These connections have now moved past a straightforward association with the organic frameworks to impact the natural procedures that can prompt tissue recovery.

3. _____________ is the first process involved in Biomaterial-Tissue interaction.
a) Foreign Body Response
b) Elongation
c) Adhesion
d) Replication
View Answer

Answer: a
Explanation: All in all, the nature of the cooperation among biomaterials and tissues in the body can be portrayed by two primary procedures. The foreign body response (FBR), is particularly activated on account of an implantable gadget so as to shield the body from the remote material. Once the biomaterial gadget or platform is embedded in the body, a tissue/biomaterial interface straightforwardly structures and causes a progression of incendiary reactions.
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4. There is the formation of the fibrous capsule when the Biomaterial-Tissue implant is implanted in the body.
a) TRUE
b) FALSE
View Answer

Answer: a
Explanation: Foreign body reaction (FBR) begins with an intense stage that can last as long as a few days. During this stage, leukocytes are actuated to the implantation site, and some development elements and cytokines are created. Monocytes are likewise enrolled, which separate into macrophages. After this period, which is the situation when the biomaterial is embedded in the body, an unending outside body response is activated. This is when lymphocytes and macrophages show up, notwithstanding the advancement of veins that are essential for wound mending and tissue recovery.

5. ____________ is one of the most important aspects of biomaterial-tissue interactions.
a) Biocompatibility
b) Bioavailability
c) Bioequivalence
d) Bioluminescence
View Answer

Answer: a
Explanation: Biomaterials should be able to mimic the native cell microenvironment and to control the spatiotemporal secretion of growth factors and morphogens.
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6. There are three major types of biomaterial-tissue interactions.
a) TRUE
b) FALSE
View Answer

Answer: b
Explanation: There are two major types of biomaterial-tissue interactions, namely local and systemic interactions. The local interactions are the ones taking place at the implant site, e.g., inflammation, infection, tumorigenesis, etc. Systemic interactions affect the organism as a whole triggering immune responses. These two usually are the reasons for the device associated complications like biomaterial’s failure.

7. Scaffolds acquire stability and strength from the cells.
a) TRUE
b) FALSE
View Answer

Answer: b
Explanation: The scaffolds provide mechanical integrity and stability, the adhesive substrate, and soluble factors for the cells in newly formed tissues.
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Sanfoundry Global Education & Learning Series – Tissue Engineering.

To practice all areas of Tissue Engineering, here is complete set of 1000+ Multiple Choice Questions and Answers.

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He is Linux Kernel Developer & SAN Architect and is passionate about competency developments in these areas. He lives in Bangalore and delivers focused training sessions to IT professionals in Linux Kernel, Linux Debugging, Linux Device Drivers, Linux Networking, Linux Storage, Advanced C Programming, SAN Storage Technologies, SCSI Internals & Storage Protocols such as iSCSI & Fiber Channel. Stay connected with him @ LinkedIn | Youtube | Instagram | Facebook | Twitter