Immunology Questions and Answers – Inflammatory Responses and Natural Killer Cells

This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Inflammatory Responses and Natural Killer Cells”.

1. Tumours, Dolor, Rubor, Color Functio laesa are the symptoms of ___________
a) Inflammation
b) Complement system
c) Hematopoiesis
d) Cytokine related diseases
View Answer

Answer: a
Explanation: All the above mentioned symptoms are of Inflammation. Inflammation is a complex biological response that is caused when a foreign particle enters the body tissues. This biological response is released in any of the above mentioned symptoms.

2. What is the cardinal sign called when there is redness caused due to inflammation?
a) Rubor
b) Calor
c) Tumour
d) Dolor
View Answer

Answer: a
Explanation: Rubor is nothing but redness of the body tissue due to inflammation. This is caused due to the dilation of blood vessels to the body tissue. The other symptoms, i.e., calor, tumor and dolor are different kinds of biological response which are not related to redness.

3. What is the cardinal sign called when there is pain caused due to inflammation?
a) Rubor
b) Calor
c) Tumour
d) Dolor
View Answer

Answer: d
Explanation: The pain caused due to inflammation is called the classic cardinal sign, Dolor. When there is pain there is a disruption of body tissue. The remaining symptoms show biological responses like calor-temperature, tumour-swelling and rubor-redness.
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4. What is the cardinal sign called when there is heat caused due to inflammation?
a) Rubor
b) Calor
c) Tumour
d) Dolor
View Answer

Answer: b
Explanation: Heat caused due to inflammation is the rise in temperature. Fevers are mediated by the classic inflammation caused at the site of injury or where a pathogen attacked.

5. What is the cardinal sign called when there is swelling caused due to inflammation?
a) Rubor
b) Calor
c) Tumour
d) Dolor
View Answer

Answer: c
Explanation: Swelling usually edema, that is the swelling of the body tissues caused due to inflammation. This is usually caused due to the accumulation of fluids outside the blood vessels.

6. What is the cardinal sign called when there is loss of function caused due to inflammation?
a) Rubor
b) Calor
c) Functio laesa
d) Dolor
View Answer

Answer: c
Explanation: Functio Laesa is the fifth cardinal and acute sign of inflammation. It is the medicinal term used to refer when there is a loss of function or an acute disturbance in the function.

7. Which of the following cells don’t have any specialized receptors?
a) Macrophages
b) Basophils
c) Natural Killer cells
d) Neutrophils
View Answer

Answer: c
Explanation: Natural Killer cells do not have any specialized antigen presenting receptors but they do have some surface markers like CD16 and CD57.
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8. Natural Killer cells are a part of larger group of immune cells called ________
a) T cells
b) B cells
c) Macrophages
d) Lymphocytes
View Answer

Answer: d
Explanation: Natural Killer cells are a part of the largest group of innate immune cells called Lymphocytes. The other type of the lymphocytes are T cells and B cells.

9. To which type of cell does a Natural Killer cell binds and gets activated?
a) When the cell don’t have CD3
b) When the cell don’t have class 1 MHC molecules
c) When the cell don’t have CD4
d) When the cell don’t have IL-4
View Answer

Answer: b
Explanation: Natural Killer cells bind to only those cells which lack class 1 MHC molecules. That is why they are called Natural Killers because they do not need any these molecules to present the antigen.
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10. Which of the following is the growth factor of Natural killer cells?
a) IL-2
b) IL-3
c) IL-4
d) IL-6
View Answer

Answer: a
Explanation: IL-2 or Interleukin-2 acts as the growth factor for Natural killer cells. It can enhance the responses of Natural Killer cells in vivo and can activate it in vitro.

Sanfoundry Global Education & Learning Series – Immunology.

To practice all areas of Immunology, here is complete set of 1000+ Multiple Choice Questions and Answers.

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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