Immunology Questions and Answers – Secondary Lymphoid Organs

This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Secondary Lymphoid Organs”.

1. What is the structure that separates the secondary lymphoid organs from the rest of the body?
a) Epithilial layer
b) Fibrous capsule
c) Mucosal capsule
d) Bilipid layer
View Answer

Answer: b
Explanation: The secondary lymphoid organs are highly organized structures. Fibrous capsule surrounds and separates the secondary lymphoid organs such as lymph nodes and spleen from rest of the body.

2. Full form of MALT is ____________
a) Mucosa associated lymphoid organs
b) Mucosa associated lobular organs
c) Membrane associate lymphoid organs
d) Membrane associated lobular organs
View Answer

Answer: a
Explanation: MALT (Mucosa associated lymphoid organs) is a collection of secondary lymphoid tissues which are associated with linings of some organs. These are situated in discrete locations in the body including Ganstrointestinal tract, respiratory tract etc.

3. What do the lymph vessels contain?
a) Plasma
b) Interstitial fluid
c) Lymphatic fluid
d) Lymph
View Answer

Answer: d
Explanation: Lymph is a protein rich fluid that is derived from the plasma which is the fluid component of the blood. Lymph is filled in the lymph vessels.

4. The largest lymphatic vessel is _________
a) Thoracic duct
b) Subclavian vein
c) Right lymphatic duct
d) Left lymphatic duct
View Answer

Answer: a
Explanation: Thoracic duct is the largest lymphatic vessel in the body. Interestingly, it is emptied into the left subclavian vein. The thoracic duct collects lymph from all the areas of the body except right side of the head and right arm.

5. Which of the following is not a component of the lymph nodes?
a) Lymphocytes
b) Macrophages
c) Granulocytes
d) Dendritic cells
View Answer

Answer: c
Explanation: The lymph nodes are highly organized secondary lymphoid organ which contains stromal cells which are packed with Lymphocytes, Macrophages and Dendritic cells. Granulocytes are not a part of the lymph nodes.

6. The three concentric regions defining the lymph nodes are: cortex, ________ and medulla.
a) Hypercortex
b) Hypocortex
c) Metacortex
d) Paracortex
View Answer

Answer: d
Explanation: The lymph nodes are divided into three concentric regions which are Cortex, Paracortex and Medulla. Each of these regions has a separate microenvironment where distinct cells reside.

7. State true or false.
Paracortex is the region of the lymph node which is rich in B – cells.
a) True
b) False
View Answer

Answer: b
Explanation: In lymph nodes, paracortex is the region rich in T – cells. However, cortex contains a large number of B – cells and some dendritic cells.

8. What is the full form of FRCC?
a) Fibroblast Reticular Cell Conduit
b) Fibrinogen Reticular Cell Conduit
c) Follicular Red Cell Conduit
d) Fibroblast Red Cell Conduit
View Answer

Answer: a
Explanation: FRCC (Fibroblast Reticular Cell Conduit) is a network of stromal cells in the paracortex of the lymph nodes. This network aids in the guidance of T – cell movement.

9. What is the site of activation and differentiation of B – cells?
a) Bone marrow
b) Lymph nodes
c) Spleen
d) Thymus
View Answer

Answer: b
Explanation: B – cells migrate to lymph nodes after maturation in the bone marrow. The activation and differentiation of B – cells take place in the lymph nodes.

10. What is HEV?
a) High Epithelial Veins
b) High Epithelial Venules
c) High Endothelial Veins
d) High Endothelial Venules
View Answer

Answer: d
Explanation: The HEV (High Endothelial Venule) is an afferent vessel through which the naive T – cells and B – cells enter the lymph nodes. They are named so because they are lined by very tall endothelial cells.

11. How do the antigens and lymphocytes take entry in the spleen?
a) Lymphatic vessels
b) Receptors
c) Splenic artery
d) Gated channels
View Answer

Answer: c
Explanation: Spleen is a specialized secondary lymphoid organ that filters the blood and accumulates the antigens of the blood. Lymphatic vessels are not used by the spleen; instead, the antigens and the blood enter the spleen via a splenic artery and exits via a splenic vein.

12. The projections in the capsule of the spleen are called as _______
a) Mucosal lining
b) Epithelium
c) Trabeculae
d) Cuticle
View Answer

Answer: c
Explanation: The spleen is the largest secondary lymphoid organ and it is surrounded by a capsule. There are multiple projections in the spleen capsule called trabeculae.

13. The surgical removal of the spleen is called as __________
a) Splenectomy
b) Spleenotomy
c) Spleenectomy
d) Splenotomy
View Answer

Answer: a
Explanation: Splenectomy is the process of surgical removal of the spleen. People are seen to face more numbers of blood borne infections after splenectomy.

14. Which of the following is NOT MALT?
View Answer

Answer: c
Explanation: MALTs are Mucosa associated lymphoid tissues which are present in discrete regions. Specifically, they are named as NALT (Nasal associated lymphoid tissue), BALT (Bronchus associated lymphoid tissues) and GALT (Gut associated lymphoid tissue).

15. Tissues that are present at the site of infection are called as ________
a) Major lymphoid tissue
b) Primary lymphoid tissue
c) Secondary lymphoid tissue
d) Tertiary lymphoid tissue
View Answer

Answer: d
Explanation: Tertiary lymphoid tissues are the ones that are present at the site of infections. The tertiary lymphoid tissues are known to create microenvironments to organize the returning lymphocytes.

Sanfoundry Global Education & Learning Series – Immunology.

To practice all areas of Immunology, here is complete set of 1000+ Multiple Choice Questions and Answers.

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Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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