Immunology Questions and Answers – Regulation, Interactions and Ubiquinity related to Innate Immunity

This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Regulation, Interactions and Ubiquinity related to Innate Immunity”.

1. What is the neural circuit that controls the cytokine production in spleen called?
a) Inflammatory reflex
b) Inflammatory circuit
c) Spleen circuit
d) Spleen reflex
View Answer

Answer: a
Explanation: It is called Inflammatory reflex. Inflammatory reflex is a prototypical neural circuit which controls cytokine production in the spleen. The sensory and afferent arc is activated by cytokines.

2. Inflammatory reflex mediates the release of _________
a) Acetylcholine bromide
b) Acetylcholine chloride
c) Acetylcholine fluoride
d) Acetylcholine
View Answer

Answer: d
Explanation: The potentials are transmitted via vagus nerve to spleen to mediate acetylcholine release. This inturn inhibits the release of cytokine release.

3. Which nerve is involved in inflammatory reflex?
a) Abducens nerve
b) Vagus nerve
c) Splenic nerve
d) Spinal nerve
View Answer

Answer: b
Explanation: The vagus nerve (also called as cranial nerve) has a major role in the inflammatory reflex. This helps in controlling the innate immune responses during tissue injury.

4. Acetylcholine inhibits cytokine release by interacting with __________
c) CHRNA7-2
d) FYN
View Answer

Answer: b
Explanation: Acetylcholine inhibits the release of cytokine by interacting with alpha7 nicotinic acetylcholine receptors or CHRNA7. These receptors are expressed on cytokine-producing cells.

5. What is a cholinergic anti-inflammatory pathway?
a) A motor arc inflammatory reflex
b) A splenic arc inflammatory reflex
c) A sensory arc inflammatory reflex
d) An afferent arc inflammatory reflex
View Answer

Answer: a
Explanation: Cholinergic Anti-Inflammatory pathway is the inflammatory reflex of the motor arc. This pathway helps in regulating the innate immune response.

6. What are the hormones that alter the sensitivity of the immune system called?
a) Immunomodulators
b) Innate modulators
c) Adaptive modulators
d) Neurohormones
View Answer

Answer: a
Explanation: Hormones that have the capability to change the sensitivity of the immune system are called Immunomodulators. These play a vital role in immunotherapies.

7. What is Somatotropin?
a) Sex hormone
b) Growth hormone
c) Luteotropic hormone
d) Steroid hormone
View Answer

Answer: b
Explanation: Somatotropin is the growth hormone that is capable of regulating the immune responses. This is a peptide hormone and is a type of mitogen.

8. Which of the following vitamins is involved with the T cell encountering a pathogen?
a) Vitamin A
b) Vitamin D
c) Vitamin B
d) Vitamin K
View Answer

Answer: b
Explanation: T cells extend a Vitamin D receptor when it encounters a foreign pathogen. It binds to the active form of vitamin D, Calcitriol. Vitamin D plays a crucial role in activating the immune defenses.

9. Can the immune system be disturbed because of sleep deprivation?
a) Yes
b) No
View Answer

Answer: a
Explanation: The immune system is affected by sleep deprivation. It is Detrimental to immune functions. The disturbances in the immune responses can lead to an increase in slow-wave sleep.

10. Overnutrition and Undernutrition compromise the immune responses.
a) False
b) True
View Answer

Answer: b
Explanation: Overnutrition causes diseases like obesity which can affect the immune system. Undernutrition can cause lifelong impairment of the immune system.

Sanfoundry Global Education & Learning Series – Immunology.

To practice all areas of Immunology, here is complete set of 1000+ Multiple Choice Questions and Answers.

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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