This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Immune System Cells – Myeloid Lineage”.
1. State true or false.
Myeloid progenitor cells and lymphoid progenitor cells are derived from different HSCs.
a) True
b) False
View Answer
Explanation: Hematopoietic stem cells are pluripotent stem cells and which have the capability to give rise to all the different kinds to blood cells. The lineage starts from the division of HSCs into myeloid progenitor cells and lymphoid progenitor cells.
2. Which of the following is NOT a type of granulocytes?
a) Eosinophils
b) Mast cells
c) Monocytes
d) Basophils
View Answer
Explanation: Granulocytes are derived from myeloid progenitor cells and give rise to Eosinophils, Mast cells, Basophils and Neutrophils. Monocytes are professional Antigen Presenting Cells which are not classified as Granulocytes.
3. Which is the most predominant type of leukocytes in the blood stream?
a) Neutrophils
b) Natural Killer Cells
c) Macrophages
d) Monocytes
View Answer
Explanation: Neutrophils are present majority in the circulating leukocytes. Their presence is about 50-70%. Their number increases even more at the time of infection.
4. The increase in the number of neutrophils at the time of infection is called as ________
a) Neutrocytosis
b) Leukocytosis
c) Neutrophilosis
d) Granulocytosis
View Answer
Explanation: The transient production of more neutrophils when there is an infection is called as leukocytosis. Leukocytosis is an indication for infection.
5. Which of these is NOT a component of Eosnophils granules?
a) Cytokines
b) Chemokines
c) Cationic proteins
d) Histamine
View Answer
Explanation: The granules of Eosinophils contain Cytokines, Chemokines, Ribonucleases and Cationic proteins. Histamines are component of Neutrophil granules.
6. Who discovered Dendritic Cells?
a) Ralph Steinman
b) Sune Karl
c) Thomas Henry
d) John Ray
View Answer
Explanation: Ralph Steinman was the one who discovered the role of dendritic cells in the immune system in 1970s. He was awarded Nobel Prize in Physiology and Medicine for the same in 2011.
7. Full form of APC is ________
a) Antibody Phagocytic Cells
b) Antigen Presenting Cells
c) Antibody Presenting Cells
d) Antigen Phagocytic Cells
View Answer
Explanation: Full form of APCs is Antigen Presenting Cells. These are specialized phagocytic cells which have the function of antigen presentation to the antibodies.
8. Mark true or false.
Dentritic Cells and Follicular Dendritic Cells have different functions from each other.
a) True
b) False
View Answer
Explanation: Dentritic Cells and Follicular Dendritic Cells have different origins and hence, have different functions. Follicular Dendritic Cells are located in lymph follicles, which gave them their name. They do not function as Antigen Presenting Cells.
9. Where in human body are the Follicular Dendritic Cells located?
a) Graafian Follicle
b) Lymph Follicles
c) Lymph Nodes
d) Bone Marrow
View Answer
Explanation: Follicular Dendritic cells are borne in the lymph follicles. They have got their name because of their origin. They play an important role in the maturation of B-cells.
10. Which of the following mammalian myeloid cells are enucleated?
a) Erythrocytes
b) Mast cells
c) Neutrophills
d) Dendritic cells
View Answer
Explanation: Erythrocytes are mature red blood cells which release their nuclei at the maturation step in mammals. The precursors of Erythrocytes contain nucleus which is condensed and extruded from the cell.
11. Which of the following cell types give rise to Platelets?
a) Mast Cells
b) Monocytes
c) Macrophages
d) Megakaryocytes
View Answer
Explanation: Megakaryocytes are large cells of the myeloid lineage which fragment and give rise to many platelets in the blood. These platelets help in blood coagulation. Mast cells, Monocytes and Macrophages have different functions.
12. Which of the following process gives rise to all the cells of immune system?
a) Hematopoiesis
b) Hematocytosis
c) Hemopoiesis
d) Hemocytosis
View Answer
Explanation: Hematopoiesis is the process by which all the cells of the immune system and the red blood cells develop. The stem cells from which all these cells arise are the Hematopoietic Stem Cells.
13. Which of these is NOT a property of stem cells?
a) Self renewal
b) Differentiation
c) Immortality
d) Pluripotency
View Answer
Explanation: All the stem cells are mortal; they come to senescence and undergo apoptosis. Self-renewal, differentiation and pluripotency are all important properties of the stem cells.
14. Which of these is NOT a function of Neutrophil?
a) Tissue remodeling
b) Antiviral activity
c) Vasodilation
d) Inflammation
View Answer
Explanation: The functions of Neutrophils include inflammation, regulation of proteases, vasodilation, tissue remodeling and direct harm to pathogens. Antiviral activity is a function of Eosinophils.
15. Which of the following represents an Erythrocyte?
a) Figure I
b) Figure II
c) Figure III
d) Figure IV
View Answer
Explanation: Erythrocytes are enucleated cells which are represented by figure III. Figure IV represents a normal nucleated cell; figure II represents a nucleated cell with lobed cytoplasm and figure I is representing a cell with condensed nucleus.
Sanfoundry Global Education & Learning Series – Immunology.
To practice all areas of Immunology, here is complete set of 1000+ Multiple Choice Questions and Answers.
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