This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Innate Immunity”.
1. Natural Killer cells are involved in Innate immunity. True or False?
a) True
b) False
View Answer
Explanation: Innate Immunity cells include most of the lymphocytes and natural killer cells are a type of lymphocytes. They play a major role in host rejections.
2. Using which process does a phagocyte reaches to the site of inflammation?
a) Diffusion
b) Brownian motion
c) Chemotaxis
d) Vasotaxis
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Explanation: Phagocytes migrate to the site of infection and inflammation via chemotaxis. They bind the target cell by releasing the receptor molecules when they come in contact.
3. What are temperature rising chemicals of the body called?
a) Thermogenics
b) Thermophiles
c) Mesogens
d) Pyrogens
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Explanation: Pyrogens are produced and released by bacteria when they enter the body and are released into the blood. They raise the temperature of the body causing fever.
4. Pattern Recognition Receptors( PRRs ) found in the cytoplasm of the host cell includes _________
a) IFN-gamma
b) TNF
c) IL-2
d) TLR-4
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Explanation: TLR-4 is found on the cytoplasm of the host cell. It belongs to the Pattern Recognition Receptor (PRR) family. They recognize PAMPs and thus provide the first line of defence against defences.
5. Which of the following cells is capable of phagocytosis?
a) Neutrophil
b) Basophil
c) Lymphocyte
d) Eosinophil
View Answer
Explanation: Neutrophils are phagocytic cells from the options given above. Rest of the blood cells are not phagocytic in nature. Macrophages are also phagocytic cells.
6. Does innate immunity response depend on the conserved features of pathogens in any way?
a) Yes
b) No
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Explanation: Yes, the innate immunity responses rely on the body’s capability of recognizing the conserved features of pathogens. And these pathogens are to be not present in uninfected host.
7. Is activation of complement pathway is one of the innate immune responses? Yes or No?
a) Yes
b) No
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Explanation: The activation of the complement pathway is one of the functions of the innate immune system. When this pathway is activated clearance of the body dead cells occurs.
8. Mast cells show the immune response against _______
a) Allergies
b) Tumours
c) Disease causing pathogens
d) Suppressing the complement pathway
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Explanation: Mast cells, as a part of innate immune responses, act against allergic reactions. They are involved in the IgE-Mast cell mediated immune response.
9. Which of the following cells are involved in innate immune responses as well as adaptive immune responses?
a) Neutrophils
b) Macrophages
c) Natural Killer cells
d) Dendritic cells
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Explanation: Dendritic cells are involved in antigen presentation where they are served as a link between innate immune system and adaptive immunity system.
10. Which of the following species use a defense mechanism called the restriction modification system?
a) Virus
b) Bacteria
c) Plants
d) Fungi
View Answer
Explanation: Bacteria are the organisms that utilize the restriction modification system. They use this defense mechanism against pathogens like bacteriophages.
Sanfoundry Global Education & Learning Series – Immunology.
To practice all areas of Immunology, here is complete set of 1000+ Multiple Choice Questions and Answers.
