This set of Immunology Multiple Choice Questions & Answers (MCQs) focuses on “Phagocytosis”.
1. What is a phagocyte?
a) The pouch in which a consumed cell or cellular debris has been contained
b) The cell that engulfs another cell or debris by phagocytosis
c) Any immune cell
d) A macrophage
View Answer
Explanation: A phagocyte is a cell that engulfs another cell or cell debris by phagocytosis. These include macrophages, neutrophils and all other granulocytes.
2. Which of the following cells are not a part of mononuclear phagocytosis?
a) Mesangial cells
b) Kupffer cells
c) Endothelial cells
d) Monocytes
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Explanation: Mononuclear phagocytosis is a type of function carried out mostly by the granulocytes and other connective tissue macrophages. Endothelial cells doesn’t fall into this category.
3. Which of the following cells is capable of phagocytosis?
a) Neutrophil
b) Basophil
c) Lymphocyte
d) Eosinophil
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Explanation: Neutrophils are phagocytic cells from the options given above. Rest of the blood cells are not phagocytic in nature. Macrophages are also phagocytic cells.
4. Macrophages are the dominating cells to take action in the early stage of infections.
a) True
b) False
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Explanation: Macrophages predominate the early stages of infections. These early actions are mediated by many other cytokines and factors like interferons, DAMPs, TNFs, etc,.
5. What stage of phagocytosis is being shown in the below image?
a) Attachment
b) Ingestion
c) Killing
d) Degradation
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Explanation: There are four stages of phagocytosis. The above image shows the degradation stage of it. It occurs after the phagocytic cell has killed the target cell.
6. The vesicle that is formed when a phagocyte engulfs the target cell is called a ___________
a) Phagocyte
b) Phagosome
c) Endosome
d) Exosome
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Explanation: The vesicle that is formed around the target cell is called the phagosome. This is formed when the phagocyte engulfs the target cell to kill it.
7. How is a phagosome destroyed?
a) By protein denaturation
b) By pressure applications
c) By fusing with the lysosome
d) By altering the pH
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Explanation: A phagosome is destroyed when it fuses with a lysosome. This lysosome releases lytic enzymes which can digest the phagosome.
8. In which of the following species, phagocytosis is meant for feeding?
a) Eukaryotes
b) Fungi
c) Bacteria
d) Protists
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Explanation: In protists, phagocytosis is a means of feeding process. It is also meant as part or of all the nourishment for the organism.
9. A substance that can enhance phagocytosis is called (a/an) _________
a) Phagocyte
b) Phagosome
c) Opsonin
d) Lysosome
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Explanation: Opsonin is the substance which can be a protein or any antibody that enhances the phagocytosis. This process is called opsonization.
10. Phagocytosis is a part of ________
a) Endocytosis
b) Exocytosis
c) Pinocytosis
d) Transcytosis
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Explanation: Phagocytosis is a type of Endocytosis. There are three types of endocytosis-phagocytosis, pinocytosis and receptor mediated phagocytosis. Phagocytosis is a process of eating and Pinocytosis is a process of drinking.
11. Which of the following is an opsonin?
a) C3a
b) C3b
c) C4a
d) C4b
View Answer
Explanation: In innate immunity, C3b is believed to opsonize, i.e., it enhances the ability of the target cell to get phagocytosed. It can tag pathogens and apoptotic cells.
Sanfoundry Global Education & Learning Series – Immunology.
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