This set of Cell Biology Multiple Choice Questions & Answers (MCQs) focuses on “Metabolism”.
1. Catabolic pathways result in _______________ of the molecules.
a) assembly
b) functionalization
c) conformation
d) disassembly
View Answer
Explanation: Catabolism refers to the disassembly of complex molecules to form simpler products. Catabolism hence serves two roles: providing raw materials for synthesis of products and making chemical energy available for survival of a cell.
2. Energy released by catabolic pathways is stored in how many forms?
a) 1
b) 2
c) 3
d) 4
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Explanation: Energy released by catabolic pathways is stored primarily in two forms: high energy phosphates like adenosine triphosphate and high energy electrons (NADPH).
3. Anabolic pathways are energy-requiring.
a) True
b) False
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Explanation: Anabolic pathways lead to the formation of complex molecules from simpler raw products. These require chemical energy which is supplied by the exergonic catabolic pathways.
4. How many molecules of ATP are formed per molecule of oxidation of glucose?
a) 12
b) 24
c) 36
d) 48
View Answer
Explanation: In one cycle of glycolysis, 6 ATP is obtained. Each molecule of glucose gives 2 pyruvate which corresponds to 6 ATP. There is also formation of 2 acetyl-CoA molecules which is about 24 ATP. Thus each molecule of Glucose give 36 ATP. ( Note that about 34 ATP molecules are consumed in glycolysis thus the net yield is 2 ATP).
5. The TCA cycle occurs in which region of a prokaryotic cell?
a) cytosol
b) mitochondria
c) ribsomes
d) golgi complex
View Answer
Explanation: There are two stages in the catabolism of glucose namely glycolysis which occurs in the cytosol and tricarboxylic acid (TCA) cycle which occurs in the cytosol of prokaryotes and mitochondria of eukaryotes.
6. Glycolysis begins with which of the following reactions?
a) reduction
b) oxidation
c) phosphorylation
d) acidification
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Explanation: Glycolysis begins with the addition of a sugar molecule to a phosphate group. Phosphorylation activates the sugar molecule to take part in later steps of the process and also reduce the concentration of glucose in the cytoplasm, promoting continued diffusion from blood to the cell.
7. NAD is a _________
a) enzyme
b) cofactor
c) protein
d) nucleoside
View Answer
Explanation: Nicotinamide adenine dinucleotide is a non-protein cofactor called coenzyme. NAD plays a key role in the metabolism of the cell by donating and accepting electrons.
8. NAD⁺ can be derived from which vitamin?
a) A
b) C
c) Riboflavin
d) Niacin
View Answer
Explanation: NAD⁺ is the reduced state of the coenzyme NAD. It is derived from the vitamin niacin and is loosely bound to the enzyme dehydrogenase.
9. In fermentation, which of the following is regenerated?
a) Starch
b) Oxygen
c) NAD⁺
d) NADH
View Answer
Explanation: Cells are able to regenerate NAD⁺ by fermentation. In this process the transfer of electrons take place from NADH to pyruvate or to a compound derived from pyruvate.
10. In case of repeated contraction, muscle cells regenerate NAD⁺ by converting pyruvate to _____________
a) glycogen
b) lactate
c) starch
d) cellulose
View Answer
Explanation: In case of repeated contraction, the oxygen levels drop down and make it difficult to keep up with the cell’s metabolic demands. Under these conditions, skeletal muscle cells regenerate NAD⁺ by converting pyruvate to lactate.
11. Yeast cells convert pyruvate to lactate.
a) True
b) False
View Answer
Explanation: Unlike the cells of skeletal muscles, which convert pyruvate to lactate in case of low oxygen supply; the yeast cells convert pyruvate to ethanol.
12. A cell’s reservoir of NADPH represents its _______________
a) oxidation state
b) oxidation power
c) tensile strength
d) reducing power
View Answer
Explanation: A cell’s reservoir of NADPH is a measure of its reducing power and the usable energy. NADPH is a compound similar to NADH but with an additional phosphate group.
13. How many mechanisms exist for altering the shape of an enzyme, playing a role in regulating glucose oxidation?
a) 1
b) 2
c) 3
d) 4
View Answer
Explanation: For regulating glucose oxidation, there are two mechanisms that are responsible for altering the shape of an enzyme’s active site namely covalent modification and allosteric modification.
14. Protein kinases are responsible for transferring which group?
a) oxygen
b) carbon
c) amino
d) phosphate
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Explanation: Protein kinases are a class of enzymes that transfer phosphate group to other proteins (covalent modification). These are hence vital in hormone action, cell division and gene expression.
15. How many types of protein kinases are there?
a) 1
b) 2
c) 3
d) 4
View Answer
Explanation: There are two types of protein kinases: one adds phosphate group to tyrosine residues in a protein and the other adds phosphate group to serine or threonine residues.
Sanfoundry Global Education & Learning Series – Cell Biology.
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