This set of Molecular Endocrinology Multiple Choice Questions & Answers (MCQs) focuses on “Pituitary Tropic Hormones – Set 2”.
1. Which pituitary tropic hormone plays an important role in the maturation of spermatozoa in males?
a) FSH
b) TSH
c) LH
d) Oxytocin
View Answer
Explanation: FSH induces seminal tubules and testicular development in males. This hormone also plays a major role in spermatozoa maturation. Indirect structural and metabolic support for the development of spermatogonia into mature spermatids is provided by pituitary-derived FSH through its membrane-bound receptor in Sertoli cells.
2. Which pituitary tropic hormone is also known as interstitial cells stimulating hormone (ICSH)?
a) FSH
b) LH
c) Vasopressin
d) Oxytocin
View Answer
Explanation: The hormone produced by gonadotropic cells in the anterior pituitary gland is known as luteinizing hormone. LH (luteinizing hormone) hormone is otherwise known as interstitial cells stimulating hormone (ICSH). It activates the final maturation of Graafian follicle and induces ovulation.
3. Which pituitary tropic hormone in combination with luteinizing hormone (LH) helps in the production of estrogen and progesterone?
a) Vasopressin
b) Oxytocin
c) Luteotropic hormone (LTH)
d) Thyrotropic Hormone or Thyroid Stimulating Hormone (TSH)
View Answer
Explanation: Luteinizing hormone, in combination with luteotropic hormone (LTH), is associated with the corpus luteum development of estrogen and progesterone. It also helps to establish and grow the corpus luteum for cell luteinization.
4. FSH by itself can cause complete formation of spermatozoa during spermatogenesis.
a) True
b) False
View Answer
Explanation: FSH alone does not induce complete spermatozoa formation. Testosterone is needed for its completion as well. FSH thus tends to initiate the spermatogenesis proliferation process, and testosterone is required for spermatozoa to finally mature.
5. The growth and functional activities of Leydig cells are induced by LH hormone.
a) True
b) False
View Answer
Explanation: Testosterone is developed by the Leydig interstitial cells, when LH from the pituitary gland activates the testes. LH therefore promotes the growth and functional activity of interstitial Leydig cells and thus secrete testicular androgen in males.
6. Which hormone is secreted by the pituitary gland, in a stage preceding to ovulation in females?
a) FSH
b) LH
c) TSH
d) Vasopressin
View Answer
Explanation: With FSH, LH works to induce follicle swelling before ovulation. It should be remembered that the pituitary secretes significant quantities of LH, called ovulatory surge, during the day immediately preceding ovulation.
7. Which cells are stimulated by the luteinizing hormone (LH) for the production of testosterone in males?
a) Leydig cells
b) Pancreatic beta cells
c) Sperm cells
d) Sertoli cells
View Answer
Explanation: Adjacent to the seminiferous tubules in the testicle, Leydig cells, also known as Leydig interstitial cells, are normally seen. Testosterone is produced from the Leydig interstitial cells. The amount of testosterone secreted ranges roughly in comparison to the available amount of LH because it activates the testes.
8. Which hormones secreted from the pituitary gland affect the transport of nerve impulses?
a) Vasopressin
b) Oxytocin
c) TSH
d) Endorphins
View Answer
Explanation: Endorphins are a group of polypeptides that affect the propagation of nerve impulse. They are also recognized as opioids because they bind to receptors that bind opioids such as morphine and play a significant role in the experience of pain.
9. The firstly discovered opioids which are released from the pituitary gland are known as?
a) Encephalin
b) Zintec
c) Kinetin
d) Leptins
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Explanation: Two pentapeptides in the brain were the first opioids identified and were called ‘encephalins.’ They consist of Methionine-encephalin and leucine-encephalin. The pituitary gland releases beta-endorphins into the bloodstream in reaction to noxious and stressful stimuli, while the brain pulls endogenous opioids into the cerebrospinal fluid.
10. Which among the following is the precursor of endorphin which is released from the pituitary gland?
a) LSH
b) Beta-LPH
c) Alpha-LPH
d) Inulin
View Answer
Explanation: The precursor for endorphins, all three forms of alpha, beta and gamma, and even for beta-MSH, is the molecule called beta-lipoprotein (Beta-LPH). Beta-Lipoprotein (beta-LPH) is derived from the pro-opiomelanocortin peptide precursor molecule.
11. Which pituitary tropic hormone plays a role in the regulation of pain in humans?
a) TSH
b) FSH
c) Endorphins
d) LH
View Answer
Explanation: One of five classes of naturally occurring opioid peptides that modulate pain and dyspnea is beta-endorphins. Endorphins bind to the same CNS receptors as morphine opiates, and they play a part in the experience of pain in endogenous regulation. They have higher action for pain relief than morphine.
12. Which among the following are the three types of endorphins available?
a) Endorphin 1, Endorphin 2 and Endorphin 3
b) Endorphin alpha, Endorphin beta and Endorphin omega
c) Beta Endorphin, Delta Endorphin and Gamma Endorphin
d) Alpha Endorphin, Beta Endorphin and Gamma Endorphin
View Answer
Explanation: Three forms of endorphins are available, namely alpha, beta, and gamma. Beta-endorphin is supplied by the 31 amino acid chain at the C-terminus of Beta-LPH (obtained from POMC). In humans and other species, endorphins are endogenous opioid neuropeptides and peptide hormones.
Sanfoundry Global Education & Learning Series – Molecular Endocrinology.
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