This set of Biochemical Engineering Multiple Choice Questions & Answers (MCQs) focuses on “Genetic Recombination”.
1. Identify the stage at which genetic recombination occurs in the case of eukaryotes?
a) Mitosis
b) Meiosis
c) Binary fission
d) Cloning
View Answer
Explanation: Genetic recombination occurs at the stage of meiosis in the case of eukaryotes. Meiosis allows the transfer of new genetic information from parents to their offspring.
2. Which of these is the stage where the homologous pairing occurs?
a) Zygotene
b) Diplotene
c) Pachytene
d) Leptotene
View Answer
Explanation: Pachytene is a phase under Prophase I of meiosis I where homologous pairing and crossing over occurs. The exchange of information from non-sister chromatids results in genetic recombination.
3. Recombination occurs at any location of the chromosome. The frequency of recombination between two locations is the same.
a) True
b) False
View Answer
Explanation: The frequency of recombination is different based on the distance separating them. If the distance is high then the crossing over is also high.
4. Identify the technique:-
“Genetic material is copied from one chromosome to another without changing the parent chromosome”
a) Bacterial recombination
b) Non-homologous recombination
c) Chromosomal crossover
d) Gene conversion
View Answer
Explanation: Genetic material is copied from one chromosome to another without changing the parent chromosome in gene conversion technique. Gene conversion occurs at a higher rate during meiosis.
5. ____________ mechanism changes antibody from one class to another.
a) Gene conversion
b) Immunoglobulin class switching
c) Non-homologous recombination
d) Crossing over
View Answer
Explanation: Immunoglobulin class switching mechanism changes antibody from one class to another. B-cells arid this recombination involved.
6. Identify the technique:
“Genetic recombination is used for the addition, deletion or complete change of an organism.”
a) Recombinant DNA technology
b) Gene targeting
c) Biomedical research
d) Protein engineering
View Answer
Explanation: Gene targeting is used for the addition, deletion or complete change of an organism. Gene targeting is a very good example of genetic engineering.
7. What is protein engineering?
a) Identify newly developed proteins
b) Indentifying the protein
c) Indentifying the structure of proteins
d) Calculating the number of scaffolds of proteins
View Answer
Explanation: Protein engineering is based on genetic recombination. Here, we can identify the newly developed proteins easily.
8. Which of the following statements are true regarding recombination repair?
• Recombination repair is done on the damaged DNA during Mitosis and Meiosis • Recombination repair is done on the damage caused only by chemical cross-linking agents • Repaired by REC • Deficiency of BRCA1 leads to cancer
a) Statement (i) and (ii) are correct
b) Statement (ii) and (iii) are correct
c) Statement (i) and (iv) are correct
d) Statement (ii) and (iv) are correct
View Answer
Explanation: Recombination repair is done on the DNA damaged during mitosis and meiosis. The main causes of this damage are UV light, X-rays, Chemical cross-linking agents. The deficiencies of gene products required for HRR are BRCA1 and BRCA2.
9. Which of these is anti-hemophilic factor synthesized using recombinant DNA technology?
a) Factor VI
b) Factor VII
c) Factor VIII
d) Factor IX
View Answer
Explanation: Factor VIII is the blood clotting protein. It is coded by the F8 gene and defects in it are called hemophilia A.
10. What is the first successful genetically engineered product?
a) Insulin
b) Somatotropin
c) Tobacco
d) Growth hormone
View Answer
Explanation: Insulin is first genetically engineered drug. It is used to treat diabetes.
11. Identify the organism whose mutant is pest-resistant?
a) Salmonella typhimurium
b) Agrobacterium tumafaciens
c) TMV mosaic virus
d) Bacillus thurenginesis
View Answer
Explanation: Mutant of Salmonella typhimurium is pest-resistant. It contains a target gene of glyphosphate which can be easily mutated.
12. What are Lymphokines?
a) These are proteins which regulate immune system of the human body
b) These are proteins which regulate circulatory system of the human body
c) These are proteins which regulate lymph system of the human body
d) These are proteins which regulate nervous system of the human body
View Answer
Explanation: Lymphokines are proteins which regulate the immune system of a human body. It is very helpful in the case of AIDS because it can stimulate the multiplication of lymphocytes.
13. Which of these vectors are widely used for studying specialized transduction?
a) Bacteriophage
b) Lambda phage
c) PUC19 vector
d) M13 mp vector
View Answer
Explanation: Lambda phage is a bacteriophage which infects E.coli. Its major importance is in the study of specialized transduction. It has application in the red operon because it contains red-alpha, beta and gamma proteins.
14. Which of these is the Biochemical products obtained from recombinant DNA technology?
a) Medicine
b) Vaccine
c) Food
d) All of the above mentioned
View Answer
Explanation: Recombinant DNA technology is used to obtain biochemical products of medicines like insulin, growth hormones. HIV vaccines, golden rice, pest-resistance crops can all be obtained by this technology.
15. Non-homologous recombination can lead to cancer.
a) True
b) False
View Answer
Explanation: The statement non-homologous recombination can lead to cancer is true. Here recombination occurs between DNA sequences of no homology.
Sanfoundry Global Education & Learning Series – Biochemical Engineering
To practice all areas of Biochemical Engineering, here is complete set of 1000+ Multiple Choice Questions and Answers.
If you find a mistake in question / option / answer, kindly take a screenshot and email to [email protected]
