This set of Biochemical Engineering Multiple Choice Questions & Answers (MCQs) focuses on “Biological Basics – Viruses”.
1. What is the symmetry of virions of T-even phages that infect E.coli?
a) Tetranal symmetry
b) Trinal symmetry
c) Binal symmetry
d) Pentanal symmetry
View Answer
Explanation: These virions of even T-even phages have a binal symmetry. They have a head similar to an icosahedron and a tail similar to helical.
2. Influenza virus consists of two spikes: – Neuraminidase and Hemagglutinin proteins. What is the function of Hemaggluttinin?
a) Release mature virions from the cells of the host
b) Release mature virions from the RBC’s
c) Bind with RBC’s and clump them together
d) Release mature virions from RBC’s and clump the cells to each other
View Answer
Explanation: Functions of Neuraminidase is to release of mature virions from its host cell. Function of Hemagglutinin proteins is to bind virions to red blood cells and clump the cells together. This process is a called hemagglutination.
3. Which phage multiplies immediately upon entering into the host cell?
a) Oncovirus
b) Virulent
c) Lambda bacteriophage
d) Temperate
View Answer
Explanation: Virulent phage begins multiplying immediately upon entering into the host cell and releases the new viruses by lysis of the host. T4 is an example of a virulent phage.
4. Which form of bacteria remains within the host?
a) Prophage
b) Anaplasia
c) Induction
d) Lysogens
View Answer
Explanation: The form of the virus that remains within its host is called a Prophage. A Prophage is simply the viral nucleic acid either integrated into the bacterial chromosome or free in the cytoplasm.
5. Which of this virus is responsible for the generation of liver cancer?
a) Hepatitis B
b) HPV
c) Hepatitis C
d) HTLV-1
View Answer
Explanation:
| VIRUS | CANCER |
| Hepatitis B | Hepatocellular carcinoma |
| HPV | Cervical cancer |
| Hepatitis C | Liver cancer |
| HTLV-1 | T-cell leukemia |
6. What dose of Serial Dilution has to be prepared to kill 50% of host cells?
a) Cytophytic dose
b) Infectious dose
c) Lesions dose
d) Lethal dose
View Answer
Explanation: The lethal dose is the dilution which contains a concentration of virions to destroy 50% of the host cells or organisms. The infectious dose is the dose that causes 50% of the host organisms to infect.
7. Which type of satellite is used to encode its own capsid?
a) Satellite virus
b) Satellite DNA
c) Satellite RNA
d) Satellite
View Answer
Explanation: Satellites are of three types: satellite virus, satellite RNA, and satellite DNA. Satellite viruses encode their own capsid proteins. Satellite RNA and DNA do not encode their capsid protein.
8. Which enzyme production is increased when the cII protein levels are high?
a) DNA dependent RNA polymerase
b) Integrase
c) RNA polymerase I
d) RNA polymerase II
View Answer
Explanation: The transcription of int gene increases when the cII protein levels are high. This increases the production of the enzyme integrase.
9. What is the function of lambda PAQ?
a) Transcriptional activator
b) Generate mRNA for integrase
c) Generation of antisense strand
d) Promoter for transcription
View Answer
Explanation: Lambda PAQ means lambda promoter for Anti-Q mRNA. Transcription of PAQ generates an antisense RNA which binds with the Q mRNA to prevent translation.
10. What is the self-defense system of bacteria and archea called?
a) Temperate system
b) ACS system
c) Lethal system
d) CAS system
View Answer
Explanation: It is called the CAS system. This system was discovered to analyze bacterial and archaeal genomes in order to identify the sets of repeated sequences separated by short spacers.
11. HIV is a result of infection by the retrovirus.
a) True
b) False
View Answer
Explanation: True. Retroviruses replicate their genomes and synthesize mRNA using an intermediate. The intermediate is a double stranded DNA which is formed by a multifunctional enzyme called reverse transcriptase.
Sanfoundry Global Education & Learning Series – Biochemical Engineering
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