Basic Biotechnology Questions and Answers – Genetics – Systems Biology

This set of Basic Biotechnology Multiple Choice Questions & Answers (MCQs) focuses on “Genetics – Systems Biology”.

1. What can be constructed by reversing the nucleotide sequence of a gene?
a) Antisense gene
b) Complementary gene
c) Protein
d) DNA
View Answer

Answer: a
Explanation: Genes can be silenced by antisense technology. Antisense gene can be constructed by reversing the nucleotide sequence of the gene. This technique has found various applications in biotechnology.

2. Transcription of an antisense gene produces ________
a) Single stranded DNA molecule
b) DNA molecule
c) RNA molecule
d) Protein
View Answer

Answer: c
Explanation: Transcription always produces RNA molecules. Translation results in the production of Proteins. So, transcription of an antisense gene produces RNA molecule.

3. The sense and anti-sense RNA strands are ______
a) Antiparallel
b) Parallel
c) Trapezoidal
d) Circular
View Answer

Answer: a
Explanation: The sense and anti-sense RNA strands are antiparallel. Genes can be silenced by antisense technology. Antisense gene can be constructed by reversing the nucleotide sequence of the gene.
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4. Where is antisense technology used on?
a) Radioactive decay
b) Biochemical Analysis
c) Transgenic Plants
d) Perfumeries
View Answer

Answer: c
Explanation: Antisense technology was used in transgenic plants. It was to control ripening. An example is FlavrSavr Tomato.

5. When was the gene expressing small non-protein coding RNAs in small worms detected?
a) 1993
b) 2013
c) 1973
d) 1953
View Answer

Answer: a
Explanation: In 1993 a gene expressing small non- protein coding RNAs in a small worm, was detected. It was observed in a small worm, Coenorhabditis elegans. It led to the discovery of micro RNAs.

6. What can regulate up to 30% of mammalian genes?
a) Anti proteins
b) Venoms
c) DNA Ligase
d) Micro RNAs
View Answer

Answer: d
Explanation: Previously unknown classes of endogenous, single stranded 19-21 nucleotide molecules were micro RNAs. It is used in gene regulation. It can regulate up to 30% of mammalian gene.

7. Who discovered micro RNAs?
a) Gregor Mendel
b) Charles Darwin
c) Robert Koch
d) Craig Mells
View Answer

Answer: d
Explanation: Micro RNAs were discovered by Craig Mells. He was awarded in 2006 with the Nobel Prize. It was for Physiology and Medicine.
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8. What allow us to determine the biological sequences that make up the cell?
a) Genomic sequences
b) Cell membrane
c) Chloroplast
d) Golgi apparatus
View Answer

Answer: a
Explanation: Genomic sequences allow us to determine the biological components. These make up the cell. Sometimes, even the whole organism.

9. What examines the interaction of components from molecular level to form the whole organism?
a) Systems biology
b) Microbiology
c) Softwares
d) Data Analytics
View Answer

Answer: a
Explanation: Systems biology is a new discipline. It deals with the components and their interaction and how they form networks. Ultimately hoe the whole organism is formed.
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10. What are biological systems primarily composed of?
a) Information genes
b) Synapses
c) Tendons
d) Ligament
View Answer

Answer: a
Explanation: Systems biology does not concentrate on individual genes or proteins. It encompasses the behavior of all components in a particular system. Biological systems are primarily composed of information genes.

11. What control the expression of genes?
a) Regulatory components
b) Chloroplast
c) Golgi apparatus
d) Endoplasmic reticulum
View Answer

Answer: a
Explanation: There are encoded products and regulatory genes. These control the expression of the gene. Systems biology interprets complex biological systems.

12. What has catapulted molecular biology into the existing realms of systems biology?
a) Genomics and proteomics
b) Anthropology
c) Psychology
d) Physiology
View Answer

Answer: a
Explanation: Systems analysis has been used historically. Genomics and proteomics have catapulted molecular biology. Its into the exciting realms of systems biology.

Sanfoundry Global Education & Learning Series – Basic Biotechnology.

To practice all areas of Basic Biotechnology, here is complete set of Multiple Choice Questions and Answers.

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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