Analytical Instrumentation Interview Questions

Here are the top 50 commonly asked questions in Analytical Instrumentation interviews. Whether you’re just starting your preparation or need a quick refresher, these questions and answers will help you tackle your interview with confidence.

Basic Analytical Instrumentation Interview Questions with Answers

1. What is Analytical Instrumentation?

The detailed study of analyzing, quantifying, and separating biological and chemical components is called analytical instrumentation.

2. Why study of Analytical Instrumentation is important?

The study of analytical instrumentation enables us to analyze any biochemical component and test its purity.

3. Who is the father of modern Analytical Instrumentation?

Malmstadt is considered as father of modern analytical instrumentation.

4. When was Analytical Instrumentation discovered?

In late 19th century analytical instrumentation was discovered for advancement in chemistry field.

5. Which events led to the attraction of Analytical Instrumentation?

Spectroscopic and microscopic techniques were needed for analysis of biochemical components and that led to attraction of analytical instrumentation.

6. Which scientists led to the development of Analytical Instrumentation?

Torbern Bergman, Justus Von Liebig, Gaustav Kirchhoff and Robert Bunsen were the three scientists that led to the development of analytical instrumentation.


7. Who termed the coin “Analytical Instrumentation”?

Torbern Bergman termed the coin “Analytical Instrumentation” for qualitative analysis of chemical elements.

8. How Analytical Instrumentation earlier were aiding in Chemistry?

In the earlier times, analytical instruments were developed and used to analyze elements like cesium and rubidium.

9. What is the importance of Analytical Instrumentation?

Analytical instrumentation is a field of biotechnology which helps in qualitative and quantitative assessment of elements and compounds.

10. How Analytical Instrumentation is linked with molecular biology?

Molecular entities like DNA or RNA are analyzed using analytical instruments like microscopes and spectroscopes.

11. How difficult is Analytical Instrumentation?

Analytical instrumentation is a complex field which deals with different kinds of analyzing instruments. These instruments are hard to understand and complex in use.

12. What are the main goals of Analytical Instrumentation?

There are few main goals of analytical instrumentation. First is qualitative and quantitative analysis of matters and second is producing highly pure materials.

13. What are the applications of Analytical Instrumentation?

There are various applications of analytical instrumentation in forensic science, life science, food, and beverage industries etc.

14. What is the significance of Analytical Instrumentation?

Analytical instruments are very significant in nature. These instruments save time by minimizing the length of reactions. These instruments quickly analyze elements.

15. What is the use of Analytical Instrumentation in day-to-day life?

Analytical instruments like mirror and lenses are used in vehicles, homes, technical instruments etc.


16. How Analytical Instrumentation is linked with Biochemistry?

Biochemistry includes all the biochemical elements and structures that are quantized and analyzed with the help of bioanalytical instruments.

17. What are the properties of Analytical Instrumentation?

There are few properties of analytical instrumentation such as measuring and quantifying elements in by following a standard set of rules and using instruments in a well-controlled manner.

18. What are the characteristics of Analytical Instrumentation?

This instrumentation can precisely measure and analyze components through various techniques and deliver product of highest quality.

19. What are the advantages of Analytical Instrumentation?

Analytical instrumentation includes microscopic and spectroscopic techniques which helps is analyzing elements, structures etc.

20. What are the disadvantages of Analytical Instrumentation?

The analytical instruments are not cost effective and sometimes these instruments show errors in their results.


Intermediate Analytical Instrumentation Interview Questions with Answers

21. What is the learning objective of analytical instrumentation?

The field of analytical instrumentation develops knowledge of bioanalytical methods. It improves the learning skills by exposing the learner towards analytical tools for studying biological and non-biological aspects.

22. What is microscopy?

Microscopy is an important part in analytical instrumentation. It includes microscopes to view objects which cannot be seen with our naked eyes.

23. What is spectroscopy?

The study of light emission, light absorption, and radiation from all the matters in the world is called spectroscopy. Spectroscopy is an important technique in analytical instrumentation.

24. What is photometry?

The study of measurement of light intensity with respect to human eye is called photometry. Unit of light intensity is candela.

25. What is spectrometry?

The study of interactions among matter and light, reactions along with wavelength and radiation intensity measurement is called spectrometry.

26. What is the basic principle of electrophoresis?

The basic principle of electrophoresis is that molecules are separated based on difference in size and charge. This occurs under the influence of an electric field.

27. What is the basic principle of photometry?

The basic principle of photometry is the measurement of light absorbing analytes in a solution. Light is measured with the help of different objects.

28. What is the basic principle of spectroscopy?

The production, measurement and interpretation of different spectra which arises from interaction between electromagnetic radiation (ER) and matter.

29. What is the basic principle of microscopy?

The basic principle of microscopy includes image formation of specimen along with magnification and resolution factors. Image formed can be seen with the help of microscope.

30. What is radiochemical technique?

The technique used in analytical instrumentation, focusing on sample analysis for finding out radioactivity is called radiochemical technique.

31. What is chromatogram?

The graphical representation of separated elements, used for identification of compounds is called chromatogram.

32. What is chromatography?

The process of separation of elements from a mixture of compounds is called chromatography. It is one of the important techniques in modern analytical instrumentation.

33. What is basic electrophoresis?

The technique which is used to separate proteins molecules, RNA and DNA is called basic electrophoresis. Electrophoresis is of various types depending on various factors.

34. What are the elements of an analytical instrument?

There are various elements of an analytical instruments such as information source, display system, transducer, signal conditioner etc.

35. What is composition analysis?

The analysis of elements presence, quality of elements and their relative quantity is called composition analysis.

36. What type of meters are used in analytical instrumentation?

Different types of meters are used in analytical instrumentation such as calorimeter, refractometer, spectrophotometer etc.

37. What is an analyzer?

The device which is used in analytical instrumentation to analyze elements or compounds is called analyzer. Different analyzers are used according to the state of molecules.

38. What is conductivity in analytical instrumentation?

There are certain elements which possesses the ability to conduct electric current in analytical techniques. This property is called conductivity.

39. What is conductance measurement in analytical instrumentation?

The process of measuring the conductivity of a solution is called conductance measurement. Conductance is reciprocal of resistance.

40. What is the use of conductivity cell?

Conductivity cell is helpful in conductivity measurement. Electrical resistance is measured in case of chemicals or pure water. Conductivity cell is an important instrument in analytical instrumentation.

41. What is absorption?

The process of absorption of atoms or molecules by letting them enter their volume is called absorption. Absorption is different from adsorption in many ways.

42. What is emission spectrum?

The range of frequency spectrum of electromagnetic radiation, emitted by an atoms or molecule’s transition in different energy levels is called emission spectrum.

43. What is scattering of light?

The phenomenon of light rays getting deviated from their original path on striking any object is called scattering of light.

44. What is convergence in analytical instrumentation?

The phenomenon of light rays getting converged at one point is called convergence in analytical instrumentation. This phenomenon is important in case of image formation.

45. What is divergence theorem in analytical instrumentation?

The phenomenon of light rays getting diverged into many is called divergence in analytical instrumentation. This phenomenon is important in case of image formation.

46. What are pH analyzers?

The devices used to measure the pH of elements or compounds in analytical processes are called pH analyzers. PH analyzers have a wide range of numbers in measuring pH.

47. What is a sensor?

An analytical instrument that reacts to the presence of an analyte is called a sensor. These are important elements in analytical devices.

48. What is a detector?

A device which converts radiation into electrical signal is called a detector. These are of two types: thermal detector and photon detector.

49. What are electrodes?

Conductors used in analytical methods that contacts non-metallic parts are called electrodes. These are of two types: reactive electrodes and inert electrodes.

50. What is calibration method?

The process of ensuring that device used in analytical techniques gives accurate results is called calibration method. Calibration method is mostly in instruments that measure different parameters.

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Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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