7 Best Books on Biopharmaceutical Technology

“Biotechnology and Biopharmaceutical Manufacturing, Processing, and Preservation (Drug Manufacturing Technology Series)” Book Review: The volume details the practices involved in large-scale processing of biotechnological products. It encompasses methodologies for processing and bulk storage preservation, as well as strategies to enhance process efficiency for various products and manufacturing facilities. The book delves into large-scale chromatography for distilling biomolecules during manufacturing and lyophilization of protein pharmaceuticals. Additionally, it includes a case study on the mechanics of blow-fill-seal processing and provides insight into the economic and cost factors involved in bioprocess engineering.

“GFP Whole Cell Microbial Biosensors: Scale-up and scale-down effects on biopharmaceutical processes” Book Review: The book describes recent advances in bioreactor machinery that adhere to the scaling-out principle, where multiple cultures are carried out simultaneously in controlled environments for screening purposes. This involves the development of various mini-bioreactor concepts that use the scaling-out principle, such as bioreactors with working volumes ranging from 1 to 100 mL, equipped with control devices. The research includes a thorough analysis of the chemical engineering similarities between conventional stirred bioreactors and their miniature counterparts.

“Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines” Book Review: The book details strategies for overcoming obstacles that hinder the effective delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines to their intended site of action. It discusses various challenges encountered in delivering biopharmaceuticals, such as immune responses, adjuvants, and vaccine delivery systems. The text provides numerous examples of delivery systems used for various biopharmaceuticals, as well as innovative formulation approaches for peptide and protein injectables. Additionally, it includes a critical evaluation of delivery technologies for biopharmaceuticals and highlights the methods utilized by researchers to ensure efficient delivery of this promising new category of drugs.

“Biopharmaceuticals: Biochemistry and Biotechnology” Book Review: The book offers a comprehensible and up-to-date overview of the scientific and medicinal applications of biopharmaceutical products. It elucidates the properties of therapeutic substances such as interferons, interleukins, growth factors, hormones, antibodies, and vaccines. The book primarily concentrates on polypeptide-based therapeutic agents and also covers the potential uses of nucleic acids in gene therapy and antisense methods. Its intended audience is advanced undergraduate or postgraduate students studying biotechnology, biochemistry, pharmaceutical science, or medicine.

“Quality by Design for Biopharmaceutical Drug Product Development” Book Review: This book is a comprehensive guide for professionals in the biopharmaceutical industry. The book covers essential topics such as process understanding, risk assessment, and design space development. It explores critical aspects of drug product development, including formulation, process development, and validation. Chapters delve into analytical methods, control strategies, and regulatory considerations. With practical examples and case studies, the authors highlight the application of Quality by Design principles. This book is a valuable resource for researchers, scientists, and professionals involved in biopharmaceutical drug product development.

“Pharmaceutical Engineering Guides for New and Renovated Facilities: Biopharmaceutical Manufacturing Facilities” Book Review: This book is a comprehensive resource for professionals involved in the design and construction of biopharmaceutical manufacturing facilities. The book covers a wide range of topics including facility planning, process design, cleanroom design, utilities and systems, equipment selection, and commissioning and qualification. Each chapter provides practical guidance, best practices, and industry standards to ensure the successful implementation of biopharmaceutical manufacturing facilities. With its valuable insights and detailed information, this book serves as an essential guide for engineers, architects, project managers, and other stakeholders in the pharmaceutical industry.