Virology Questions and Answers – Humans Viruses – Picornaviridae and Togaviridae

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This set of Virology Multiple Choice Questions & Answers (MCQs) focuses on “Humans Viruses – Picornaviridae and Togaviridae”.

1. The genome of picornavirus consists of _____________ protein linked to its 5’ end.
a) VPa
b) VPg
c) VPk
d) VPd
View Answer

Answer: b
Explanation: The genome of picornavirus consists of VPg protein linked covalently to its 5’ end. It consists of a single linear molecule of single-stranded RNA of positive polarity and polyadenylated at its 3’ end.
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2. Which of the following viruses multiply in the nose?
a) Enterovirus
b) Hepatovirus
c) Rhinovirus
d) Reovirus
View Answer

Answer: c
Explanation: Rhinoviruses are the viruses of the family Picornaviridae that multiply in the nose. They are acid-labile and they also have a substantially greater buoyant density by cesium chloride equilibrium gradient centrifugation.

3. The size of the genome of togavirus is _____________
a) 13 – 17 kb
b) 4 – 5 kb
c) 20 – 21 kb
d) 11 – 12 kb
View Answer

Answer: d
Explanation: The size of the genome of togavirus is 11 – 12 kilobases and it consists of a single linear molecule of single-stranded polarity that is infectious. It is capped at 5’ end and polyadenylated at 3’ end and is easily inactivated by disinfectants.
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4. Which of the following virus is spread by Anopheles funestus?
a) Chikungunya virus
b) Mayaro virus
c) O’nyong-nyong virus
d) Ross River virus
View Answer

Answer: c
Explanation: O’nyong-nyong virus is spread by Anopheles funestus and A gambiae. It is the only known human arboviral pathogen with anopheline mosquitoes as a vector. The vertebrate reservoir of the virus is unknown.

5. Mayaro viruses are spread by _______________
a) Anopheles funestus
b) Anopheles gambiae
c) Aedes aegypti
d) Haemagogus
View Answer

Answer: d
Explanation: Mayaro viruses are spread by Haemagogus mosquitoes from a primate reservoir. It occurs in the forested region of Central and South America and causes a widespread human infection.
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6. Vero cells are used to culture rubella virus.
a) True
b) False
View Answer

Answer: a
Explanation: Vero cells are used to culture rubella viruses. RK-13 can also be used to culture the rubella viruses however, the growth is slow without conspicuous cytopathic effects. The isolation in the cell culture is only used as a supplementary method of diagnosing rubella from throat swabs.

7. The vertebrate reservoir of the chikungunya virus is monkeys.
a) True
b) False
View Answer

Answer: a
Explanation: The vertebrate reservoir of the chikungunya virus are monkeys and humans. The chikungunya virus normally lives in monkeys and humans and turns them infectious. The disease may or may not transfer from the reservoir to other living beings.
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Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He is Linux Kernel Developer & SAN Architect and is passionate about competency developments in these areas. He lives in Bangalore and delivers focused training sessions to IT professionals in Linux Kernel, Linux Debugging, Linux Device Drivers, Linux Networking, Linux Storage, Advanced C Programming, SAN Storage Technologies, SCSI Internals & Storage Protocols such as iSCSI & Fiber Channel. Stay connected with him @ LinkedIn | Youtube | Instagram | Facebook | Twitter