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Molecular Biology Multiple Choice Questions | MCQs | Quiz

Molecular Biology Interview Questions and Answers
Practice Molecular Biology questions and answers for interviews, campus placements, online tests, aptitude tests, quizzes and competitive exams.

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•   Nucleic Acid Molecules
•   Nucleic Acids Structures
•   Double Stranded DNA
•   Central Dogma Outlines
•   Ribosomes - Genetic Code
•   Various RNA Classes - 1
•   Various RNA Classes - 2
•   Genome Organization - 1
•   Genome Organization - 2
•   Genome Organization - 3
•   Eukaryotic DNA Features
•   Stem & Loop Structures
•   DNA Fragments Separation
•   DNA Helical Structures
•   DNA Topology - 1
•   DNA Topology - 2
•   DNA Topology - 3
•   Chromatin Centromere
•   DNA Manipulation
•   DNA & RNA Hybridization
•   PCR Fundamentals
•   Inverse PCR & RAPD
•   Reverse Transcriptase PCR
•   Chain Termination Principle
•   Automated Sequencing
•   DNA Replication
•   DNA Polymerase - 1
•   DNA Polymerase - 2
•   DNA Synthesis Precursors
•   Complete Replication Form
•   Chromosome Replication
•   Replicon Concept
•   Replicating Linear DNA
•   Genes Expressed-RNA - 1
•   Genes Expressed-RNA - 2
•   Gene Recognizing
•   Message Manufacturing - 1
•   Message Manufacturing - 2
•   RNA Polymerase
•   Genetic Code - 1
•   Genetic Code - 2
•   Reverse Transcription
•   RNA Processing
•   Coding & Non-Coding RNA
•   Ribosomal Processing
•   Eukaryotic Messenger RNA
•   Introns Removal from RNA-1
•   Introns Removal from RNA-2
•   Introns Removal from RNA-3
•   Alternative Splicing Forms
•   mRNA Degradation
•   Protein Synthesis - 1
•   Protein Synthesis - 2
•   Amino Acids Proteins
•   Cell's Decoding Machine - 1
•   Cell's Decoding Machine - 2
•   Three Possible Frames
•   Polypeptide Elongation
•   Eukaryotic & Prokaryotic
•   Proteins Modifications
•   Proteins Degradation
•   Gene Regulation
•   Regulation Levels
•   Activators & Repressors
•   Transcriptional Regulation-1
•   Transcriptional Regulation-2
•   RNAs - Gene Regulation
•   Eukaryotic DNA Controls-1
•   Eukaryotic DNA Controls-2
•   X-Chromosomes Inactivation
•   Most Mobile DNA Elements
•   Transposable Elements - 1
•   Transposable Elements - 2
•   Plasmids Properties
•   Plasmid DNA Replicate - 1
•   Plasmid DNA Replicate - 2
•   Plasmids Helping Host Cell
•   Transferring Ti Plasmids - 1
•   Transferring Ti Plasmids - 2
•   DNA & RNA Libraries
•   Engineered Genes
•   Genetic Mutations Types
•   Chemical Mutagen Damage
•   DNA Repair Overview
•   Site-Directed Mutagenesis
•   Homologous Recombination
•   Site-Specific Recombination
•   Higher Organisms - 1
•   Higher Organisms - 2

Best Reference Books

Molecular Biology Books
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Molecular Biology Questions and Answers – RNA Polymerase Knows Where to Stop

Posted on April 19, 2018 by Manish

This set of Molecular Biology Multiple Choice Questions & Answers (MCQs) focuses on “RNA Polymerase Knows Where to Stop”.

1. The most common signal for termination of transcription is self complementation.
a) True
b) False
View Answer

Answer: a
Explanation: Yes, the most common signal for termination of transcription is self complementation. This self – complementation leads to the formation of a hairpin loop. It is also known as the Rho independent termination.
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2. The stem of the hairpin loop of RNA consists mostly of _____________
a) A, T
b) G, C
c) A, G
d) C, T
View Answer

Answer: b
Explanation: The stem of the hairpin loop of RNA consists mostly of G, C. This makes the structure more stable and thus facilitating proper termination.

3. The hairpin structure generated in the RNA is followed by a stretch of oligonucleotide complementary to the base ____________
a) A
b) T
c) G
d) C
View Answer

Answer: a
Explanation: The RNA hairpin is followed by a sequence of many “U” residues. Thus the complementary stretch of nucleotides in the DNA strand is adenine or “A”.

4. A stretch of which nucleotide in the DNA acts as the termination signal?
a) Poly G
b) Poly C
c) Poly T
d) Poly A
View Answer

Answer: d
Explanation: A hairpin loop followed by a stretch of oligo U nucleotides acts as the termination sequence. This subsequent stretch of the “U” residue pairs weakly to the “A” residues of the DNA thus favoring easy dissociation.
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5. The rho protein has ____________ subunit.
a) 4
b) 6
c) 8
d) 10
View Answer

Answer: b
Explanation: The rho protein is a hexameric protein containing 6 subunits. This protein is known to mediate transcription and is known as the Rho dependent transcription.

6. The rho proteins are ATP independent proteins.
a) True
b) False
View Answer

Answer: b
Explanation: The rho protein is an ATP dependent protein. It uses the hydrolysis of ATP to terminate the transcription in the presence of a single stranded RNA.

7. The rho protein binds to the RNA recognizes special structure. It consists of ____________ nucleotides.
a) 32
b) 48
c) 40
d) 72
View Answer

Answer: c
Explanation: The rho protein binds to the RNA recognizes special structure. It consists of 40 nucleotides. Rho moves along the nascent RNA towards the transcription complex and helps terminate the RNA synthesis.
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8. The rut sites are rich in ____________ residues.
a) A
b) T
c) G
d) C
View Answer

Answer: d
Explanation: The rut sites are special sequences used by the Rho protein to bind to terminate the RNA synthesis. These stretches of RNA do not fold into any secondary structure and is rich in “C” residues.

9. The rho protein can even bind within operons to terminate transcription.
a) True
b) False
View Answer

Answer: b
Explanation: The Rho protein fails to bind to any transcript of RNA that is being translated. Thus rho protein cannot bind within operons to terminate transcription and binds beyond the operon or gene to terminate transcription.

Sanfoundry Global Education & Learning Series – Molecular Biology.

To practice all areas of Molecular Biology, here is complete set of 1000+ Multiple Choice Questions and Answers.

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» Next Page - Molecular Biology Questions and Answers – The Genetic Code – 1

« Molecular Biology Questions and Answers – Manufacturing the Message – 2
Molecular Biology Questions and Answers – The Genetic Code – 1 »
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Deep Dive @ Sanfoundry:

  1. Bioinformatics Questions and Answers
  2. Biochemistry Questions and Answers
  3. Molecular Biology Questions and Answers
  4. Molecular Biology Questions and Answers – Transcriptional Regulation in Eukaryotes is More Complex than in Prokaryotes – 1
  5. Molecular Biology Questions and Answers – Palindromes, Inverted Repeats and Stem and Loop Structures
  6. Molecular Biology Questions and Answers – Genome Organization – 3
  7. Molecular Biology Questions and Answers – RNA is Processed in Several Ways
  8. Molecular Biology Questions and Answers – The Genetic Code – 2
  9. Molecular Biology Questions and Answers – Genes Are Expressed by Making RNA – 2
  10. Molecular Biology Questions and Answers – DNA Polymerase Elongates DNA Strands, Complete Replication Form Complex
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He is Linux Kernel Developer and SAN Architect and is passionate about competency developments in these areas. He lives in Bangalore and delivers focused training sessions to IT professionals in Linux Kernel, Linux Debugging, Linux Device Drivers, Linux Networking, Linux Storage & Cluster Administration, Advanced C Programming, SAN Storage Technologies, SCSI Internals and Storage Protocols such as iSCSI & Fiber Channel. Stay connected with him below:
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