Molecular Biology Internship

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Sanfoundry offers internships in "Molecular Biology". Read the complete details below regarding the internship requirements, eligibility criterior and the application process.

Pre-requisite / Skillset for Molecular Biology Internship

1. Intern must have the ability to describe the basic structure and biochemistry of nucleic acids and proteins and discriminate between them.

2. Should be capable of identifying the principles of DNA replication, transcription and translation and explain how they relate to each other.

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3. Should be able to discuss clearly about gene organization and mechanisms of control the gene expression in various organisms.

4. Must have the ability to articulate applications of molecular biology in the modern world.

5. Should be familiar with the cell and molecular biology of both Prokaryotes and Eukaryotes.

6. Require knowledge on methods of cloning, construction of DNA libraries and applications of rDNA technology.

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7. Require basic fundamental knowledge and explore skills in molecular biology and become aware of the complexity and harmony of the cells.

8. Should be able to emphasize the molecular mechanism of DNA replication, repair, transcription, protein synthesis and gene regulation in various organisms.

9. Adequate knowledge on molecular genetics is required.

10. Must be familiar with the basics of Molecular Biology and Genetic engineering.

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11. Basic knowledge on replication, transcription and translation is required.


Molecular Biology Internship Test

Intern has to take Molecular Biology internship test in which they will be asked 50 multiple-choice questions. They have to score grade A or A* on this test to be eligible for the internship. Here’s a sample set of questions on the Molecular Biology topic.

1. What is the major type of RNA produced in the cell required for translation?
(A) mRNA
(B) tRNA
(C) rRNA
(D) siRNA
View Answer

Answer: C
Explanation: Generally, rRNA is of 4 types 28S, 5.8S, 18S and 5S. These subunits comprises the 80% of the total amount of RNA produced in a cell and are majorly required for translation as these rRNAs along with proteins form ribosomes which reads the codes for translation.

2. Which one of the following is not a function of a nucleotide?
(A) Nucleic acid monomer
(B) Ribozyme
(C) Energy carrier molecules
(D) Receptors
View Answer

Answer: D
Explanation: Nucleotides do not form receptor molecules. Receptor molecules are generally polysaccharide molecules or protein molecules that can have structural configurations. Energy carrying nucleotide molecules such as ATP helps binding and unbinding of signal molecules to these receptors thus facilitating different biological functions.
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3. Levene investigated and found that the nucleic acid is composed of poly-nucleotides and each nucleotide is composed of one base, a sugar molecule and a phosphate. This was performed on the genome of________________
(A) Bacteria
(B) Fungi
(C) WBCs
(D) Yeast
View Answer

Answer: D
Explanation: Levene placed his initial proposal of nucleic acids being composed of nucleotides and nucleotides being composed of one of the four bases, a phosphate and a sugar molecule in 1919. He gathered all his evidence regarding the structure were from the repeated experiments of hydrolysis and analysis of the yeast nucleic acid.

4. Amino acids prior to their incorporation into polypeptide must be attached to a special adaptor molecule. Who proved this and when?
(A) Francis H. Crick in 1955
(B) Paul C. Zamecnic and Maholon B. Hoagland in 1957
(C) James Watson and Francis H. Crick in 1953
(D) Linus Pauling in 1950
View Answer

Answer: B
Explanation: In 1955 Francis H. Crick proposed that prior to the incorporation of amino acids in polypeptide chain they must be attached to an adapter molecule that can interact with the three-nucleotide long coding units of mRNA. This was finally proved in 1957 by Paul C. Zamecnic and Maholon B. Hoagland. They demonstrated that amino acids were carried by the transfer RNAs (tRNA) to the ribosome for its transfer to the growing polypeptide chain.

5. How many channels are present in the ribosome?
(A) 2
(B) 3
(C) 4
(D) 5
View Answer

Answer: B
Explanation: There are three channels present in the smaller subunit of the ribosome which facilitates the entering and exit of the mRNA. The third channel is for the exit of the growing polypeptide chain.

Practice the full set of Molecular Biology Multiple Choice Questions before applying for the internship.


How to apply for the Molecular Biology Internship

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1. Read the Sanfoundry Internship FAQs

2. Take the Molecular Biology Internship Test

3. Submit the Internship Application Form

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He is Linux Kernel Developer & SAN Architect and is passionate about competency developments in these areas. He lives in Bangalore and delivers focused training sessions to IT professionals in Linux Kernel, Linux Debugging, Linux Device Drivers, Linux Networking, Linux Storage, Advanced C Programming, SAN Storage Technologies, SCSI Internals & Storage Protocols such as iSCSI & Fiber Channel. Stay connected with him @ LinkedIn | Youtube | Instagram | Facebook | Twitter