Pre-requisite / Skillset for Bioprocess Engineering Internship
1. Intern should have the ability to select the appropriate bioreactor configurations and operation modes based upon the nature of bioproducts and cell lines and other process criteria.
2. Capable of applying modeling and simulation of bioprocesses so as to reduce costs and to enhance the quality of products and systems.
3. Intern must be able to identify and summarize the effect of change in unit’s operations and its impact on the process.
4. Capable of integrating research lab and industry; identifying problems and seeking practical solutions for large scale implementation of Biotechnology.
5. Must be aware of bioengineering skills for the production of biochemical product using integrated biochemical processes.
6. Should be capable of describing the factors affecting secondary metabolite production and its industrial importance.
7. Basics of bioreactor engineering must be known.
8. Must be capable of designing various statistical problems.
9. Should be able to examine traditional unit operations, as well as new concepts and emerging technology that is likely to benefit biochemical product recovery in the future.
10. Intern must have the ability to illustrate how emerging technologies would benefit the bio chemical product recovery and show the likely benefits it would have over the traditional operations.
11. Intern should be able to analyse both analytical and process validation issues that are critical to successful manufacturing.
12. Must be able to define the fundamentals of downstream processing for biochemical product recovery.
13. Require good knowledge on the topics like the concepts of secondary metabolite production, the strategies for biochemical process synthesis, biochemical product recovery.
Bioprocess Engineering Internship Test
Intern has to take Bioprocess Engineering internship test in which they will be asked 50 multiple-choice questions. They have to score grade A or A* on this test to be eligible for the internship. Here’s a sample set of questions on the Bioprocess Engineering topic.
1. Why Penicillin does not affect the human body when taken?
(A) Because it is a Broad spectrum antibiotic
(B) Because it is a Narrow spectrum antibiotic
(C) Because it is an analgesic
(D) Because it is a Narcotic drug
Explanation: Penicillin is the Narrow spectrum antibiotic that only kills the specific bacteria or microorganisms and not the normal bacteria or microorganisms present in Human body, in this way human body is unaffected.
2. Which type of fermentation was used by Engineers to produce penicillin on large scale during World War 2?
(A) Semi-Solid Fermentation
(B) Deep-Tank Fermentation
(C) Biphasic Fermentation
(D) Solid-State Fermentation
Explanation: The Deep-Tank Batch Fermentation in which there is the application of submerged culture technique which was able to produce Penicillin of Approximately 50mg/ml which grew on large scale during World War 2.
3. Which chemical is usually used before the Bacterial transformation process?
(A) Calcium chloride
(B) Potassium chloride
(C) Ferric chloride
(D) Sodium chloride
Explanation: Before Bacterial transformation, bacteria are treated with a chemical called Calcium chloride, which causes water to enter into the cells and makes them swell. These swollen bacteria are then known as competent bacteria, which is further used in Bacterial transformation process.
4. In the case of Rota meter, which is used for measuring the water flow rate?
(A) Only one variable is involved, i.e. independent variable (the Rota meter reading)
(B) Only two variables are involved: one independent variable(the Rota meter reading) and one dependent variable (the water flow rate)
(C) Only two variables are involved: one independent variable(the water flow rate) and one dependent variable (the Rota meter reading)
(D) Only one variable is involved, i.e. independent variable (the water flow rate)
Explanation: Rota meter is a device which measures flow rate. This is done by allowing the cross-sectional area the fluid travels through to vary, causing a measurable effect, i.e. water flow rate is dependent on Rota meter.
5. What is rate-zonal centrifugation?
(A) Based on separation of particles by mass
(B) Based on separation of particles by density
(C) Based on separation of particles on solubility
(D) Based on separation of particles on size
Explanation: Rate-zonal centrifugation is a centrifugation technique employed to effectively separate particles of different sizes. Once the centrifugation is over, fractions are collected.
Practice the full set of Bioprocess Engineering Multiple Choice Questions before applying for the internship.
How to apply for the Bioprocess Engineering Internship
1. Read the Sanfoundry Internship FAQs
2. Take the Bioprocess Engineering Internship Test
3. Submit the Internship Application Form
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