logo
  • Home
  • Test & Rank
  • About
  • Training
  • Programming
  • CS
  • IT
  • IS
  • ECE
  • EEE
  • EE
  • Civil
  • Mechanical
  • Chemical
  • Metallurgy
  • Instrumentation
  • Aeronautical
  • Aerospace
  • Biotechnology
  • Mining
  • Marine
  • Agriculture
  • MCA
  • BCA
  • Internship
  • Jobs
  • Contact

Bioinformatics Multiple Choice Questions | MCQs | Quiz

Bioinformatics Interview Questions and Answers
Practice Bioinformatics questions and answers for interviews, campus placements, online tests, aptitude tests, quizzes and competitive exams.

Get Started

•   Protein Motifs
•   ↓ Motif Databases ↓
•   Regular Expressions
•   Statistical Models
•   Protein Family Databases
•   Global Sequence Alignment
•   Local Sequence Alignment
•   Motif Discovery-Sequences
•   Dot Matrix Sequence
•   Dynamic Programming
•   Scoring Matrices & Penalty
•   Alignments Assessing
•   Bayesian Statistics
•   Sequence Homology
•   Methods
•   Sequence Alignment
•   Exhaustive Algorithms
•   Heuristic Algorithms
•   Needleman - Wunsch
•   Progressive Methods
•   Iterative Methods
•   Localized Alignments
•   Aiding Alignment
•   Specific Scoring Matrices
•   Heuristic Database Search
•   BLAST
•   FASTA
•   Compare FASTA & BLAST
•   Smith - Waterman Method
•   ↓ Protein Structure ↓
•   Protein Structure Basics
•   Visualization
•   Comparison
•   Classification
•   Globular Proteins
•   Transmembrane Proteins
•   Coiled Coil Prediction
•   Homology Modeling
•   Threading Recognition
•   RNA Structures Types
•   RNA Prediction Methods
•   Ab Initio Approach
•   Comparative Approach
•   Performance Evaluation
•   Prediction Limitations
•   Stochastic Context
•   MFOLD & Energy Plots
•   RNA Genomes
•   Genome Mapping
•   Genome Sequencing
•   Genome Assembly
•   Genome Annotation
•   Comparative Genomics
•   Sequence Approaches
•   Microarray Approaches
•   SAGE & DNA Microarrays
•   Protein Expressions
•   Translational Modification
•   Protein Sorting
•   Protein Interactions
•   Phylogenetics Basics
•   Gene Vs Specie Phylogeny
•   Tree Representation Forms
•   Distance Based Methods
•   Character Based Methods
•   Phylogenetic Evaluation
•   Phylogenetic Programs
•   Parsimony Method
•   Likelihood Approach
•   Phylogenetic Predictions
•   Gene Prediction Programs
•   Prokaryote Gene Prediction
•   Eukaryotes Prediction - 1
•   Eukaryotes Prediction - 2
•   Prokaryotes & Eukaryotes
•   Prediction Algorithms - 1
•   Prediction Algorithms - 2
•   Prediction Algorithms - 3
•   Molecular Complementarity
•   Conformational Flexibility
•   Visualization Methods
•   Protein Interactions
•   Domain Interactions
•   Gene Order & Phylogeny
•   DNA Sequencing
•   Sequencing cDNA Libraries
•   Sequence Formats
•   Multiple Sequence Formats
•   Database Access Program
•   Genome Anatomy - 1
•   Genome Anatomy - 2
•   Genome Anatomy - 3
•   Gene Identification - 1
•   Gene Identification - 2
•   Gene Identification - 3
•   Comparative Genomics - 1
•   Comparative Genomics - 2
•   Genes Classification
•   Global Gene Regulation
•   Gene Function Prediction

Best Reference Books

Bioinformatics Books
« Prev Page
Next Page »

Bioinformatics Questions and Answers – Dot Matrix Sequence Comparison

Posted on February 11, 2018 by Manish

This set of Bioinformatics Multiple Choice Questions & Answers (MCQs) focuses on “Dot Matrix Sequence Comparison”.

1. Which of the following is not a software for dot plot analysis?
a) SIMMI
b) DOTLET
c) DOTMATCHER
d) LALIGN
View Answer

Answer: a
Explanation: For the purpose of dot plot interpretation there are various softwares currently present. Among these SIM is used for these kinds of alignments through dot-plot method that is wrongly abbreviated.
advertisement

2. The softwares for dot plot analysis perform several tasks. Which one of them is not performed by them?
a) Gap open penalty
b) Gap extend penalty
c) Expectation threshold
d) Change or mutate residues
View Answer

Answer: d
Explanation: The gap penalties mentioned above are for the determination of score of the aligning sequences. The change in residue barely takes place as there are number of other softwares for that purpose and also the main objective is to find the score of the alignment.

3. For palindromic sequences, what is the structure of the dot plot?
a) 2 intersecting diagonal lines at the midpoint
b) One diagonal
c) Two parallel diagonals
d) No diagonal
View Answer

Answer: a
Explanation: For perfectly aligned sequences there is a diagonal formation of dot plot. For palindromic sequences i. e. for sequences that are symmetrical from the midpoint of the sequence, there exist 2 intersecting diagonals on the plot.

4. For significantly aligning sequences what is the resulting structure on the plot?
a) Intercrossing lines
b) Crosses everywhere
c) Vertical lines
d) A diagonal and lines parallel to diagonal
View Answer

Answer: d
Explanation: If there is alignment of sequences there is a significantly bold diagonal visible on the plot. And if the is a bit imperfect, the diagonal is shattered too to an extent and forms small parallel lines to it.

5. When was this method, first described?
a) 1959
b) 1966
c) 1970
d) 1982
View Answer

Answer: c
Explanation: This method was first described in 1970. Briefly, this method involves constructing a matrix with one of the sequences to be compared running horizontally across the bottom, and the other running vertically along the left-hand side.
advertisement

6. Who were the inventors of this method?
a) Smith-Waterman
b) Margaret Preston
c) Gibbs and McIntyre
d) Needleman-Wunsch
View Answer

Answer: c
Explanation: The first computer aided sequence comparison is called “dot-matrix analysis” or simply dot-plot. The first published account of this method is by Gibbs and McIntyre (1970 The diagram, a method for comparing sequences. Eur. J. Biochem 16: 1-11).

7. Which of the following is true for EMBOSS Dottup?
a) Allows you to specify threshold
b) Doesn’t allow you to specify threshold
c) Doesn’t allow you to specify window size
d) If all cells in the window are identity, it colors in some specific cells in the window
View Answer

Answer: b
Explanation: The EMBOSS Dottup doesn’t allow you to specify threshold but allows you to specify window size. Also, if all cells in the window are identity, it colors in all the cells in the window.

8. Isolated dots that are not on the diagonal represent exact matches.
a) True
b) False
View Answer

Answer: b
Explanation: Those isolated dots represent random matches. The dots on the diagonal represent the perfect alignment and the dots with vertical and horizontal shifts show insertions and deletions.

9. Vertical frame shifts show ______ while the horizontal ones show _______
a) insertion, insertion
b) insertion, deletion
c) deletion, deletion
d) deletion, insertion
View Answer

Answer: b
Explanation: Deletion and insertion of nucleotides is quite common in alignment process. The dot plot easily represents them with vertical and horizontal shifts. And the mutations are totally out of the diagonal zone.

10. Dot plot of repeating elements would be small crosses on plot.
a) True
b) False
View Answer

Answer: False
Explanation: The repeating elements would be represented in parallel lines in repetitive manner. Better is the repetition; better is the nature of parallel lines. Also, the intersections show the pallindromic sequences.
advertisement

Sanfoundry Global Education & Learning Series – Bioinformatics.

To practice all areas of Bioinformatics, here is complete set of 1000+ Multiple Choice Questions and Answers.

« Prev Page - Bioinformatics Questions and Answers – Motif Discovery in Unaligned Sequences
» Next Page - Bioinformatics Questions and Answers – Dynamic Programming Algorithm for Sequence Alignment

« Bioinformatics Questions and Answers – Motif Discovery in Unaligned Sequences
Bioinformatics Questions and Answers – Dynamic Programming Algorithm for Sequence Alignment »
advertisement

Deep Dive @ Sanfoundry:

  1. C Programming Examples on Set & String Problems & Algorithms
  2. C# Programming Examples on Inheritance
  3. C Programming Examples on File Handling
  4. C++ Programming Examples on Computational Geometry Problems & Algorithms
  5. Java Programming Examples on Computational Geometry Problems & Algorithms
  6. C Programming Examples on Computational Geometry Problems & Algorithms
  7. C Programming Examples on Trees
  8. C Programming Examples on Matrix
  9. C# Programming Examples on Matrix
  10. Bioinformatics Questions and Answers
Manish Bhojasia
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He is Linux Kernel Developer & SAN Architect and is passionate about competency developments in these areas. He lives in Bangalore and delivers focused training sessions to IT professionals in Linux Kernel, Linux Debugging, Linux Device Drivers, Linux Networking, Linux Storage, Advanced C Programming, SAN Storage Technologies, SCSI Internals & Storage Protocols such as iSCSI & Fiber Channel. Stay connected with him @ LinkedIn | Facebook | Twitter

Best Careers

Developer Tracks
SAN Developer
Linux Kernel Developer
Linux Driver Developer
Linux Network Developer

Live Training Photos
Mentoring
Software Productivity
GDB Assignment
Sanfoundry is No. 1 choice for Deep Hands-ON Trainings in SAN, Linux & C, Kernel Programming. Our Founder has trained employees of almost all Top Companies in India such as VMware, Citrix, Oracle, Motorola, Ericsson, Aricent, HP, Intuit, Microsoft, Cisco, SAP Labs, Siemens, Symantec, Redhat, Chelsio, Cavium, ST-Micro, Samsung, LG-Soft, Wipro, TCS, HCL, IBM, Accenture, HSBC, Mphasis, Tata-Elxsi, Tata VSNL, Mindtree, Cognizant and Startups.

Best Trainings

SAN I - Technology
SAN II - Admin
Linux Fundamentals
Advanced C Training
Linux-C Debugging
System Programming
Network Programming
Linux Threads
Kernel Programming
Kernel Debugging
Linux Device Drivers

Best Reference Books

Computer Science Books
Algorithm & Programming Books
Electronics Engineering Books
Electrical Engineering Books
Chemical Engineering Books
Civil Engineering Books
Mechanical Engineering Books
Industrial Engineering Books
Instrumentation Engg Books
Metallurgical Engineering Books
All Stream Best Books

Questions and Answers

1000 C Questions & Answers
1000 C++ Questions & Answers
1000 C# Questions & Answers
1000 Java Questions & Answers
1000 Linux Questions & Answers
1000 Python Questions
1000 PHP Questions & Answers
1000 Hadoop Questions
Cloud Computing Questions
Computer Science Questions
All Stream Questions & Answers

India Internships

Computer Science Internships
Instrumentation Internships
Electronics Internships
Electrical Internships
Mechanical Internships
Industrial Internships
Systems Internships
Chemical Internships
Civil Internships
IT Internships
All Stream Internships

About Sanfoundry

About Us
Copyright
Terms
Privacy Policy
Jobs
Bangalore Training
Online Training
Developers Track
Mentoring Sessions
Contact Us
Sitemap
© 2011 Sanfoundry. All Rights Reserved.