Biochemistry Questions and Answers – Biosynthesis of Cholesterol, Steroids and Isoprenoids

This set of Biochemistry Question Bank focuses on “Biosynthesis of Cholesterol, Steroids and Isoprenoids”.

1. Generally, the receptors for steroid hormones reside at ___________
a) Nucleoplasm
b) Nuclear membrane
c) Cytoplasm
d) Plasma membrane
View Answer

Answer: a
Explanation: The receptors for steroid hormones reside at nucleoplasm.

2. Steroids have ___________
a) Sterol nucleus with two alkyl chain attached to the ring D of cholesterol
b) Sterol nucleus with two CH3 between C and D ring and A and B ring of cholesterol
c) Sterol nucleus without CH3 between C ring and D ring of cholesterol
d) Sterol nucleus but lack the alkyl chain attached to the ring D of cholesterol
View Answer

Answer: d
Explanation: Steroids have a sterol nucleus but lack the alkyl chain attached to the ring D of cholesterol.

3. Prednisolone and prednisone are chemically ___________
a) Steroids
b) Glycerol derivatives
c) Non-steroid anti-inflammatory drug
d) Amino alcohols
View Answer

Answer: a
Explanation: Prednisolone and prednisone are chemically steroids.
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4. The essential intermediates in the pathway from acetate to cholesterol are ___________
a) Acetic acid
b) Ethylene
c) Isoprene units
d) Methane
View Answer

Answer: c
Explanation: Isoprene units are the essential intermediates in the pathway from acetate to cholesterol.

5. Which is the first intermediate in cholesterol synthesis?
a) Mevalonate
b) Isoprene
c) Squalene
d) Ethylene
View Answer

Answer: a
Explanation: The first intermediate in cholesterol synthesis is mevalonate.
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6. How many carbons are present in HMG co-A?
a) 2
b) 3
c) 5
d) 6
View Answer

Answer: d
Explanation: Two molecules of acetyl co-A condense to form acetoacetyl co-A, which condenses with the third molecule of acetyl co-A to yield a six-carbon compound HMG co-A.

7. Which of the following is the major point of regulation on the pathway to cholesterol?
a) Thiolase
b) HMG co-A synthase
c) HMG co-A reductase
d) Pyruvate kinase
View Answer

Answer: c
Explanation: HMG co-A reductase is the major point of regulation on the pathway to cholesterol.
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8. Which of the following is the integral membrane protein of smooth ER?
a) Thiolase
b) HMG co-A synthase
c) HMG co-A reductase
d) Pyruvate kinase
View Answer

Answer: c
Explanation: HMG co-A reductase is the integral membrane protein of smooth ER.

9. How many carbons are present in geranyl pyrophosphate?
a) 8
b) 9
c) 10
d) 11
View Answer

Answer: c
Explanation: Geranyl pyrophosphate is a 10-carbon chain.
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10. Which of the following regulates the female reproductive cycle?
a) Progesterone
b) Testosterone
c) Estrogens
d) Glucocorticoids
View Answer

Answer: a
Explanation: Testosterone and estrogens which influence the development of secondary sexual characteristics in males and females, respectively.
Glucocorticoids help regulate gluconeogenesis and reduce the inflammatory response.

Sanfoundry Global Education & Learning Series – Biochemistry.

To practice Biochemistry Question Bank, here is complete set of 1000+ Multiple Choice Questions and Answers.

If you find a mistake in question / option / answer, kindly take a screenshot and email to [email protected]

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Manish Bhojasia - Founder & CTO at Sanfoundry
Manish Bhojasia, a technology veteran with 20+ years @ Cisco & Wipro, is Founder and CTO at Sanfoundry. He lives in Bangalore, and focuses on development of Linux Kernel, SAN Technologies, Advanced C, Data Structures & Alogrithms. Stay connected with him at LinkedIn.

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