17 Best Books on Downstream Processing

“Protein Purification: Principles, High Resolution Methods, and Applications (Methods of Biochemical Analysis Book 149)” Book Review: This book focuses on the advancements in the bioscience field and comprehensively covers various techniques for separating proteins biochemically, ranging from high-resolution liquid chromatography to the historical evolution of protein chromatography. Additionally, the book includes updated content that encompasses a wide range of topics related to protein separation.

“Product Recovery in Bioprocess Technology (Biotol Biotechnology by Open Learning)” Book Review: This is a valuable resource for professionals and students in the field of bioprocessing. The book provides the knowledge needed to understand, select, and develop strategies for the recovery of products from bioreactors. It also highlights the critical factors that must be taken into account during the final stages of product design.

“Aqueous Two Phase Extraction for Downstream Processing of Biomolecules” Book Review: This book provides an in-depth exploration of the potential of aqueous two-phase extraction (ATPE) for downstream processing of proteins or enzymes, with a focus on its potential to reduce costs associated with downstream processing in fermentation processes. The book showcases successful examples of large-scale industrial applications of ATPE while emphasizing the importance of an interdisciplinary approach that combines microbiological, biochemical, and engineering aspects for effective downstream processing. In particular, the chapter highlights the usefulness of mathematical modeling in predicting protein enzyme partitioning. Although the advantages of ATPE include the ease of adapting existing chemical or pharmaceutical extraction equipment, further research is needed to better understand drop dynamics and mass transfer in ATPSs using real fermentation broths.

“Downstream Processing of Proteins: Methods and Protocols (Methods in Biotechnology)” Book Review: This text provides a comprehensive introduction to downstream processing and isolation technology, with a particular focus on the needs of the biopharmaceutical and biotechnology industries. The book fills a gap in the available literature by covering the broad range of isolation technology in an industrial setting, rather than focusing solely on protein purification techniques. It is an important contribution to the field and will be a useful resource for undergraduate students, researchers, and industry professionals. The text is also designed to encourage greater coverage of these topics in industrial biotechnology courses.

“Protein Downstream Processing (Methods in Molecular Biology)” Book Review: This book provides step-by-step protocols, emphasizing the practical aspects of protein purification and addressing common troubleshooting and pitfalls. It covers both high and low-resolution methods, making it a comprehensive guide for scientists working in health sciences, cellular and molecular biology. Written in a concise and easily accessible format, this book is a valuable reference for advanced students and junior researchers seeking to design and implement successful protein purification strategies.

“Downstream Processing: Advances in Biochemical Engineering/Biotechnology: 26” by A Fiechter Book Review: This book is a comprehensive guidebook that provides information on the process of creating vaccines from start to finish. The book covers all types of vaccines, from processing and production to regulatory considerations. It explains the various fields involved in vaccine production, including maturation, purification, formulation, regulatory filing, and facility design. The book also describes recent advances in vaccine production technology and media, including cell culture with high cell density or fermentation. It serves as a reference guide for scientists involved in vaccine development, offering insights into the challenges, steps involved, and advanced vaccine manufacturing technologies and facility setups.

“Handbook of Downstream Processing” by E Goldberg Book Review: This is a comprehensive guidebook for professionals in biotechnology and pharmaceutical industries. It covers all aspects of downstream processing, including techniques for protein purification, isolation, and formulation. The book also covers the design and optimization of downstream processing strategies, the regulatory environment, and the latest technological advances. Written by experienced experts in the field, the handbook provides practical information and case studies to help readers navigate the challenges of downstream processing. With its broad coverage and up-to-date information, this book is an essential reference for anyone working in biotechnology and pharmaceutical industries.

“Downstream Processing of Natural Products: A Practical Handbook” Book Review: This book is intended for individuals in the biotechnology industry, including academic and industrial researchers, postgraduate students, and technicians. It is a practical guide that focuses on the challenges of isolating natural products and covers three main stages of purification. This book is a valuable resource that offers essential practical advice to anyone involved in natural product isolation.

“Natural Gas Engineering and Safety Challenges: Downstream Process, Analysis, Utilization and Safety” by G G Nasr and N E Connor Book Review: This book is a comprehensive guide for professionals and students in the gas, petroleum, and chemical engineering fields. It covers various aspects of downstream processes involved in natural gas, such as gas processing, transmission, distribution, instrumentation and measurement systems, and utilization. Additionally, the book also discusses business and management aspects, recent innovations, pipeline design and failures, and safety challenges related to fire and explosions. Case studies are included to provide practical examples, and there is a discussion of fundamental processes involved in flame and explosion mitigation, as well as future research challenges. The book will be useful to engineers, project and operations managers, planning and design engineers, as well as undergraduate and postgraduate students.

“Modeling, Control, and Optimization of Natural Gas Processing Plants” by William A Poe and Saeid Mokhatab Book Review: This book offers valuable insights into the challenges faced by plant managers and owners in the natural gas industry. The book provides practical guidance on how to optimize plant performance and efficiency, including feed gas compositions, temperatures, pressures, and throughput capacities. It is the first reference book dedicated solely to the natural gas industry and covers the latest developments in algorithms, software, and real-world case studies. The book includes multivariable control and optimization strategies, software and algorithm comparisons, and practical case studies. This reference is a must-have for anyone involved in natural gas plant operations.

“Fundamentals of Natural Gas Processing (Mechanical Engineering (CRC Press Hardcover))” by William R Parrish and Arthur J Kidnay Book Review: This is a comprehensive reference book that covers various aspects of natural gas processing, from the wellhead to the market. It offers a comprehensive overview of gas processing technology, including field operations, pipeline receiving, compression, dehydration, hydrocarbon recovery, nitrogen rejection, liquid processing, sulfur recovery, and liquefied natural gas industry. The book includes discussions on plant economics and provides ways to estimate selected measures and determine capital costs of gas processing facilities. Suitable for both technical and non-technical personnel, this book is an essential resource for those in the industry, including students and plant designers.

“Natural Gas Processing: Technology and Engineering Design” by Alireza Bahadori Book Review: This is an essential handbook for anyone seeking to stay current with traditional and innovative gas principles and techniques. This book covers the entire natural gas process and provides comprehensive information on key topics such as gas properties, flow factors, equipment selection processes, gas processing methods, plant design and engineering, and much more. The book also explores both conventional and unconventional gas resources, with practical case studies to demonstrate the application of the theory. With detailed explanations of essential calculations for equipment sizing, this reference is a must-have for gas plant managers, engineers, and contractors.

“Bioseparations Downstream Processing for Biotechnology” by Paul A Belter and E L Cussler Book Review: The book provides a concise introduction to the separation and purification of biochemicals, bridging the gap between two scientific communities by offering an introduction to bioseparations for scientists without an engineering background and for engineers with limited knowledge of chemistry. The authors support their ideas with straightforward worked examples, making bioseparation techniques easily understandable. The book covers the removal of insoluble, product isolation, purification, and cleaning.

“Downstream Processing (Advances in Biochemical Engineering/Biotechnology)” by J Bell and P Dunnill Book Review: This is an essential reference for biochemical engineers and biotechnologists. The book offers comprehensive coverage of downstream processing, including the recovery and purification of biosynthetic products from natural sources such as animal or plant tissue. It covers key topics such as the recycling of salvageable parts and the proper treatment and disposal of waste. The authors also discuss the latest technologies in the field, making this book a valuable resource for researchers, engineers, and students interested in downstream processing and its applications in drug production, diagnostics, and industrial biotechnology.

“Biotechnology for Fuels and Chemicals: The Twenty-Fourth Symposium: 105-108 (ABAB Symposium)” by Brian H Davison and Mark Finkelstein Book Review: This book summarizes the proceedings of a symposium that brought together attendees from various countries to discuss biomass-to-ethanol projects. The symposium included 48 oral presentations and 190 posters. The attendees came from all over the world, and the special topic session was sponsored by the International Energy Agency Bioenergy Program. The book covers various aspects of pretreatment, enzymatic hydrolysis, fermentation, and lignin utilization, and presenters from different countries described their country’s biomass-to-ethanol projects. Differential factors, such as the type of biomass available, were also discussed.